80621-90-5Relevant articles and documents
PRODRUG DERIVATIVES OF SUBSTITUTED TRIAZOLOPYRIDINES
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Page/Page column 136; 137, (2015/01/09)
The present invention relates to prodrug derivatives of Mps-1 kinase inhibitors, processes for their preparation, and their use for the treatment and/or prophylaxis of diseases.
CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY AND PROCESSES FOR THEIR PREPARATION
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Page/Page column 75-76, (2008/06/13)
The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administ
Synthesis of N-urethane-protected γ-amino-functionalized butenoates and tautomeric studies by means of NMR, X-ray crystallography and ab initio calculations
Detsi, Anastasia,Gavrielatos, Efstathios,Adam, Marion-Alexandra,Igglessi-Markopoulou, Olga,Markopoulos, John,Theologitis, Marcos,Reis, Heribert,Papadopoulos, Manthos
, p. 4337 - 4342 (2007/10/03)
N-Urethane-protected γ-amino-α-cyano-β-hydroxybutenoates were synthesized as potential statine analogues and the stability of their possible tautomers was assessed using NMR, X-ray crystallography and ab initio calculations. The results establish that the cis-enol tautomeric form is the most stable one both in solution (CDCl3) and in the solid phase. In full agreement with the experimental data, the theoretical calculations predicted that the cis-enol tautomer would be the minimum energy tautomer.