80632-52-6

Usage

Uses

Since the provided materials do not specify any particular applications for L-Leucine,O-sulfo-L-tyrosylglycylglycyl-L-phenylalanyl-, it is not possible to list its uses based on the given information. However, given the roles of its constituent amino acids, it can be hypothesized that L-Leucine,O-sulfo-L-tyrosylglycylglycyl-L-phenylalanyl- may have potential applications in various industries, such as pharmaceuticals, nutrition, or cosmetics, depending on its specific properties and functions once identified through further research.

InChI:InChI=1/C28H37N5O10S/c1-17(2)12-23(28(38)39)33-27(37)22(14-18-6-4-3-5-7-18)32-25(35)16-30-24(34)15-31-26(36)21(29)13-19-8-10-20(11-9-19)43-44(40,41)42/h3-11,17,21-23H,12-16,29H2,1-2H3,(H,30,34)(H,31,36)(H,32,35)(H,33,37)(H,38,39)(H,40,41,42)/t21-,22-,23-/m0/s1

Upstream product

• 1080-04-2 p-nitrophenyl sulfate 
• 58822-25-6 Leu-enkephalin 
• 16679-95-1 benzyl (S)-(1-hydrazinyl-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)carbamate 
• 130245-55-5 Z-Tyr(SO₃H)-Gly-Gly-Phe-Leu-OBzl 
• 69729-16-4 N-benzyloxycarbonyl-L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucine benzyl ester 
• 98908-58-8 Z(OMe)-Gly-Gly-Phe-Leu-OBzl 
• 69729-07-3 H-Gly-Gly-Phe-Leu-OBzl 
• 69729-15-3 N-Carbobenzoxy-L-tyrosyl azide 

Relevant academic research and scientific papers

Sulfation of various alcoholic groups by an arylsulfate sulfotransferase from desulfitobacterium hafniense and synthesis of estradiol sulfate

Bacterial arylsulfate sulfotransferases (AST) are enzymes that catalyse the transfer of a sulfate group from p-nitrophenyl sulfate (p-NPS) to a phenolic acceptor molecule. By screening of the NCBI protein database a gene coding for an AST was found in Desulfitobacterium hafniense. After expression the enzyme was purified and characterised. This AST efficiently sulfates various acceptor molecules (estrone, estradiol, enkephalin and non-phenolic alcohols) using p-NPS as sulfate donor. The purified AST has a pH optimum of 9.6, it is stable in the presence of 10% of DMSO, and depending on the conditions it has a melting temperature of up to 47°C. Surprisingly, and in great contrast to all other known bacterial ASTs, this enzyme was able to use a variety of non-phenolic alcohols as sulfate acceptor. Because of these properties, this unique enzyme is a promising tool for biotransformation processes, providing a green and simple method to specifically sulfate compounds without need for functional group protection.

Use of Dimethylformamide-Sulphur Trioxide Complex as a Sulphating Agent of Tyrosine

Dimethylformamide-sulphur trioxide (DMF-SO3) complex was found to be more suitable for tyrosine sulphation than pyridine-sulphur trioxide (Pyr-SO3) complex, the most commonly used sulphur trioxide complex for sulphation.The work-up after sulphation using