Deladumone is a novel, synthetic, and potent small molecule inhibitor that targets the enzyme dihydroorotate dehydrogenase (DHODH), which plays a crucial role in the de novo pyrimidine synthesis pathway. This pathway is essential for the proliferation of rapidly dividing cells, such as cancer cells and certain immune cells. By inhibiting DHODH, deladumone disrupts the synthesis of pyrimidines, leading to the depletion of nucleotides and ultimately causing cell death. This mechanism of action makes deladumone a potential therapeutic agent for the treatment of various diseases, including cancer and autoimmune disorders. Its ability to selectively target rapidly dividing cells also suggests that deladumone may have fewer side effects compared to traditional chemotherapy drugs, which often affect both healthy and cancerous cells.
8064-65-1
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Basic information
- Product Name: deladumone
- Synonyms: deladumone
- CAS NO:8064-65-1
- Molecular Formula: C49H72O6
- Molecular Weight: 757.09238
- EINECS: N/A
- Product Categories: N/A
- Mol File: 8064-65-1.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 503.9°C at 760 mmHg
- Flash Point: 214.2°C
- Appearance: /
- Density: N/A
- Vapor Pressure: 2.79E-10mmHg at 25°C
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: deladumone(CAS DataBase Reference)
- NIST Chemistry Reference: deladumone(8064-65-1)
- EPA Substance Registry System: deladumone(8064-65-1)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 8064-65-1(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 8064-65-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 8,0,6 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.Calculate Digit Verification of CAS Registry Number 8064-65:
(6*8)+(5*0)+(4*6)+(3*4)+(2*6)+(1*5)=101
101 % 10 = 1
So 8064-65-1 is a valid CAS Registry Number.
InChI:InChI=1/C26H40O3.C23H32O3/c1-4-5-6-7-8-24(28)29-23-12-11-21-20-10-9-18-17-19(27)13-15-25(18,2)22(20)14-16-26(21,23)3;1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h17,20-23H,4-16H2,1-3H3;7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3/t20-,21-,22-,23-,25-,26-;18?,19?,20?,21-,23-/m00/s1
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deladumone
