80653-66-3 Usage
General Description
THIAZOLE-4-CARBOTHIOIC ACID AMIDE, also known as 2-aminothiazole-4-carbothioamide, is a chemical compound with the molecular formula C4H5N3S. It is a derivative of thiazole and carbothioic acid amide, and is commonly used in organic synthesis and as a building block in the pharmaceutical industry. It has been studied for its potential applications in the development of antitumor and antifungal drugs. THIAZOLE-4-CARBOTHIOIC ACID AMIDE is a versatile chemical that can be used in a variety of chemical reactions and has potential for further research and development in medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 80653-66-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,6,5 and 3 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 80653-66:
(7*8)+(6*0)+(5*6)+(4*5)+(3*3)+(2*6)+(1*6)=133
133 % 10 = 3
So 80653-66-3 is a valid CAS Registry Number.
InChI:InChI=1/C4H4N2S2/c5-4(7)3-1-6-2-8-3/h1-2H,(H2,5,7)
80653-66-3Relevant articles and documents
Potent and orally efficacious bisthiazole-based histone deacetylase inhibitors
Chen, Fei,Chai, Hui,Su, Ming-Bo,Zhang, Yang-Ming,Li, Jia,Xie, Xin,Nan, Fa-Jun
supporting information, p. 628 - 633 (2014/07/07)
Inspired by the thiazole-thiazoline cap group in natural product largazole, a series of structurally simplified bisthiazole-based histone deacetylase inhibitors were prepared and evaluated. Compound 8f was evaluated in vivo in an experimental autoimmune encephalomyelitis (EAE) model and found to be orally efficacious in ameliorating clinical symptoms of EAE mice.
