80662-83-5Relevant articles and documents
AZOCANE AND AZONANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS
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Paragraph 0317; 0318; 0319, (2016/10/11)
Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.
Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 1. Discovery of a class C BLI for combination with imipinem
Blizzard, Timothy A.,Chen, Helen,Kim, Seongkon,Wu, Jane,Young, Katherine,Park, Young-Whan,Ogawa, Amy,Raghoobar, Susan,Painter, Ronald E.,Hairston, Nichelle,Lee, Sang Ho,Misura, Andrew,Felcetto, Tom,Fitzgerald, Paula,Sharma, Nandini,Lu, Jun,Ha, Sookhee,Hickey, Emily,Hermes, Jeff,Hammond, Milton L.
scheme or table, p. 918 - 921 (2010/08/06)
Bridged monobactam β-lactamase inhibitors were prepared and evaluated as potential partners for combination with imipenem to overcome class C β-lactamase mediated resistance. The (S)-azepine analog 2 was found to be effective in both in vitro and in vivo assays and was selected for preclinical development.
Ring transformation of 1,2,3,5,6,7-hexahydropyrrolizinium perchlorates into 1-substituted 5-oxoperhydroazocines
Sumoto,Mibu,Irie,Abe,Miyano
, p. 577 - 580 (2007/10/02)
A facile ring transformation of 1,2,3,5,6,7-hexahydropyrrolizinium perchlorates (1 and 2) to 1-substituted 5-oxoperhydroazocines (5) is described. The spectroscopic and chemical properties of these products are also presented.
