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Upstream product

• 82300-29-6 (MeO)2Trd(TpT-Bz) 
• 104579-29-5 C₅₅H₅₆N₅O₁₅P 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 17331-53-2 3'-O-benzoylthymidine 
• 104579-21-7 Phosphoric acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2,6-dichloro-phenyl ester 2-pyridin-2-yl-ethyl ester 

Relevant academic research and scientific papers

USE OF 2-(2-PYRIDYL)ETHYL GROUP AS A NEW PROTECTING GROUP OF INTERNUCLEOTIDIC PHOSPHATES IN OLIGONUCLEOTIDE SYNTHESIS

2-(2-Pyridyl)ethyl group is used as a highly selective protecting group of internucleotidic phosphates that is removable under mild conditions by treatment with CH3I in CH3CN without a side reaction such as N-alkylation.

METAL IONS AS SELECTIVE TRIGGERS FOR REMOVING OLIGODEOXYNUCLEOTIDE PHOSPHOTRIESTER PROTECTING GROUPS

The o-bromophenyl group was successfully tested as a phosphotriester protecting group for internucleotide bonds.This protecting group can be readily and selectively removed using various transition metal salts in aqueous pyridine.