80684-97-5Relevant academic research and scientific papers
Enantio- and Diastereoselectivity in the Periodate Oxidation of Sulfides Catalyzed by Bovine Serum Albumin. 2
Colonna, Stefano,Banfi, Stefano,Annunziata, Rita,Casella, Luigi
, p. 891 - 895 (1986)
The asymmetric oxidation of aliphatic, aromatic, and heterocyclic sulfides in the presence of a catalytic amount of bovine serum albumin (BSA) affords the corresponding sulfoxides with enantiomeric excess (ee) up to 80percent.The diastereoselectivity of the process has also been examined in comparison with the enzymatic oxygenation with cytochrome P-450.Electronic and CD spectral data indicate that the sulfides are not tightly bound to BSA in the reaction conditions.
