807315-40-8 Usage
Uses
Used in Organic Synthesis:
[2-(1-Methyl-1H-pyrazol-5-yl)ethyl]amine is used as a building block in the synthesis of biologically active molecules, contributing to the development of new pharmaceuticals and chemical compounds. Its unique structure allows for the creation of a diverse range of molecules with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, [2-(1-Methyl-1H-pyrazol-5-yl)ethyl]amine is utilized as a key component in the research and development of new drugs. Its ability to form various biologically active molecules makes it a valuable asset in the search for innovative therapeutic solutions.
Used in Coordination Chemistry:
As a ligand in coordination chemistry, [2-(1-Methyl-1H-pyrazol-5-yl)ethyl]amine plays a crucial role in the formation of metal complexes. These complexes have potential applications in catalysis, materials science, and other areas of chemical research.
Used in Chemical Reactions:
[2-(1-Methyl-1H-pyrazol-5-yl)ethyl]amine also serves as a reagent in various chemical reactions, facilitating the synthesis of new compounds and contributing to the advancement of chemical knowledge and technology.
Used in Drug Development:
Ongoing research into the therapeutic properties of [2-(1-Methyl-1H-pyrazol-5-yl)ethyl]amine highlights its potential use in the development of new drugs. Its unique structure and properties make it a promising candidate for further exploration and application in the medical field.
Check Digit Verification of cas no
The CAS Registry Mumber 807315-40-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,0,7,3,1 and 5 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 807315-40:
(8*8)+(7*0)+(6*7)+(5*3)+(4*1)+(3*5)+(2*4)+(1*0)=148
148 % 10 = 8
So 807315-40-8 is a valid CAS Registry Number.
807315-40-8Relevant academic research and scientific papers
Discovery of Dihydropyrrolo[1,2- a]pyrazin-3(4 H)-one-Based Second-Generation GluN2C- And GluN2D-Selective Positive Allosteric Modulators (PAMs) of the N-Methyl- d -Aspartate (NMDA) Receptor
Epplin, Matthew P.,Mohan, Ayush,Harris, Lynnea D.,Zhu, Zongjian,Strong, Katie L.,Bacsa, John,Le, Phuong,Menaldino, David S.,Traynelis, Stephen F.,Liotta, Dennis C.,Liotta, Dennis C.
, p. 7569 - 7600 (2020/08/21)
The N-methyl-d-aspartate receptor (NMDAR) is an ion channel that mediates the slow, Ca2+-permeable component of glutamatergic synaptic transmission in the central nervous system (CNS). NMDARs are known to play a significant role in basic neurological functions, and their dysfunction has been implicated in several CNS disorders. Herein, we report the discovery of second-generation GluN2C/D-selective NMDAR-positive allosteric modulators (PAMs) with a dihydropyrrolo[1,2-a]pyrazin-3(4H)-one core. The prototype, R-(+)-EU-1180-453, exhibits log unit improvements in the concentration needed to double receptor response, lipophilic efficiency, and aqueous solubility, and lowers cLogP by one log unit compared to the first-generation prototype CIQ. Additionally, R-(+)-EU-1180-453 was found to increase glutamate potency 2-fold, increase the response to maximally effective concentration of agonist 4-fold, and the racemate is brain-penetrant. These compounds are useful second-generation in vitro tools and a promising step toward in vivo tools for the study of positive modulation of GluN2C- and GluN2D-containing NMDA receptors.
New tetrahydropyrido pyrimidinecarboxylic compound or salt thereof
-
, (2016/10/08)
To provide a compound having an inhibitory activity for an androgen receptor. A tetrahydropyridopyrimidine compound represented by the following general formula (I) or a pharmaceutically acceptable thereof (in the formula, X and R are as defined in the specification).
