807329-97-1

Basic information

• Product Name: ISOPROPYLMAGNESIUM CHLORIDE LITHIUM CHL&
• Synonyms: ISOPROPYLMAGNESIUM CHLORIDE LITHIUM CHL&;Isopropylmagnesium chloride lithium chloride complex solution;Isopropylmagnesium chloride - LiCl complex, 1M in MeTHF;Isopropylmagnesium chloride lithium chloride complex solution 1.3 M in THF;Isopropylmagnesium chloride - LiCl complex, 1.3M in THF, J&KSeal
• CAS NO: 807329-97-1
• Molecular Formula: C₃H₇ClMg*ClLi
• Molecular Weight: 145.24
• Product Categories: AlkylChemical Synthesis;Grignard Reagents;Organic Bases;Organometallic Reagents;Synthetic Reagents
• Mol File: 807329-97-1.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 66℃
• Flash Point: -17 °C
• Appearance: /
• Density: 0.951 g/mL at 25 °C
• Solubility: Miscible with ethers and amines.
• Sensitive: Air & Moisture Sensitive
• CAS DataBase Reference: ISOPROPYLMAGNESIUM CHLORIDE LITHIUM CHL&(CAS DataBase Reference)
• NIST Chemistry Reference: ISOPROPYLMAGNESIUM CHLORIDE LITHIUM CHL&(807329-97-1)
• EPA Substance Registry System: ISOPROPYLMAGNESIUM CHLORIDE LITHIUM CHL&(807329-97-1)

Safety Data

• Hazard Codes: F,C
• Statements: 14/15-19-34-11
• Safety Statements: 16-26-29-33-36/37/39-43-45-8
• RIDADR: UN 3399 4.3/PG 2
• HazardClass: 4.3
• Hazardous Substances Data: 807329-97-1(Hazardous Substances Data)

Usage

Uses

Isopropylmagnesium chloride is used in the regioselective functionalization of trisubstituted pyridines, electrophilic amination for preparation of amines and functionalization of cyclopentene derivatives. It is involved in the preparation of 2,3-functionalized furans, benzofurans, and thiophenes. Further, it is used in benzylic Grignards via sulfur-magnesium exchange.

Upstream product

• 75-29-6 isopropyl chloride 
• 1068-55-9 isopropylmagnesium chloride 
• 7439-95-4 magnesium 

Downstream Products

• 1031850-02-8 (R)-(3-isopropyl-4,7,7-trimethylbicyclo[2.2.1]hept-2-en-2-yl)phenylmethanone 
• 86186-47-2 (2-isopropylcyclopent-1-en-1-yl)phenylmethanone 
• 1105707-41-2 2-(N-allyl-N-benzylamino)-N,3-dimethylbutanamide 
• 611-69-8 rac-2-methyl-1-phenylpropan-1-ol 
• 53722-39-7 N,N'-di-isopropylbenzamidine 
• 4170-69-8 isopropyl phenyl sulfoxide 
• 1674-30-2 1-phenyl-2-chloroethanol 
• 4238-09-9 phenyl isopropyl sulfone 
• 1622142-18-0 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]propane-1,2,3-triol 
• 959020-16-7 2-chloro-4-(iso-propyl)pyridine 
• 56407-98-8 (2E)-2-benzylidene-3-methylbutan-1-ol 
• 1589519-09-4 C₁₁H₁₃ClF₃N 

Relevant articles and documents

Regioselective Bromine/Magnesium Exchange for the Selective Functionalization of Polyhalogenated Arenes and Heterocycles

Using the bimetallic combination sBu2Mg?2 LiOR (R=2-ethylhexyl) in toluene enables efficient and regioselective Br/Mg exchanges with various dibromo-arenes and -heteroarenes under mild reaction conditions and provides bromo-substituted magnesiu

Nitrile-substituted 2-(oxazolinyl)-phenols: Minimalistic excited-state intramolecular proton transfer (ESIPT)-based fluorophores

Herein, we present minimalistic single-benzene, excited-state intramolecular proton transfer (ESIPT)-based fluorophores as powerful solid-state emitters. The very simple synthesis gave access to all four regioisomers of nitrile-substituted 2-(oxazolinyl)-

Thiolation of Pyridine-2-sulfonamides using Magnesium Thiolates

The thiolation of pyridine-2-sulfonamides using magnesium thiolates is reported. The ortho-functionalizations of these sulfonamides using TMPMgCl·LiCl (TMP = 2,2,6,6-tetramethylpiperidyl) followed by electrophilic quenching produced a range of 3-functiona