807342-06-9

Upstream product

• 807342-02-5 (+)-2-[[(3R,4S)-4-(4-chlorophenyl)-1-methylpiperidin-3-yl]methylsulfanyl]acetic acid methyl ester 
• 807342-01-4 (+)-(3R,4S)-4-(4-chlorophenyl)-3-(iodomethyl)-1-methylpiperidine 
• 263769-22-8 (+)-methyl 4β-(4-chlorophenyl)-1-methylpiperidine-3α-carboxylate 
• 263769-24-0 (+)-4β-(4-Chlorophenyl)-3α-(hydroxymethyl)-1-methylpiperidine 
• 74-88-4 methyl iodide 
• 807342-04-7 (+)-trans-2-[[(3R,4S)-4-(4-chlorophenyl)-1-methylpiperidin-3-yl]methylsulfanyl]ethanol 

Relevant academic research and scientific papers

DOPAMINE-, NOREPINEPHRINE- AND SEROTONIN- TRANSPORTER- SELECTIVE HETEROCYCLIC COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS

One aspect of the invention relates to piperidine compounds that are useful as inhibitors of monoamine transporters. The invention also relates to pharmaceutical compositions, comprising a piperidine compound of the invention. Another aspect of the presen

Piperidine-based nocaine/modafinil hybrid ligands as highly potent monoamine transporter inhibitors: Efficient drug discovery by rational lead hybridization

Some piperidine-based nocaine/modafinil hybrid ligands have been designed, synthesized, and found to display an improved potency at all three monoamine transporters and particularly for DAT and/or NET. Some highly active and selective monoamine transporte