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807344-35-0

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807344-35-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 807344-35-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,0,7,3,4 and 4 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 807344-35:
(8*8)+(7*0)+(6*7)+(5*3)+(4*4)+(3*4)+(2*3)+(1*5)=160
160 % 10 = 0
So 807344-35-0 is a valid CAS Registry Number.

807344-35-0Downstream Products

807344-35-0Relevant articles and documents

A bivalent ligand (KDN-21) reveals spinal δ and κ opioid receptors are organized as heterodimers that give rise to δ1 and δ2 phenotypes. Selective targeting of δ-κ heterodimers

Bhushan, Rashmi G.,Sharma, Shiv K.,Xie, Zhihua,Daniels, David J.,Portoghese, Philip S.

, p. 2969 - 2972 (2007/10/03)

In view of recent pharmacological studies suggesting the existence of δ-κ opioid receptor heterodimers/oligomers in the spinal cord, we have synthesized and evaluated (intrathecally in mice) a series of bivalent ligands (KDN series) containing κ and δ antagonist pharmacophores. Pharmacological and binding data have provided evidence for the bridging of spinal δ-κ receptor heterodimers by KDN-21 and for their identification as δ1 and κ2. The selectivity profile of KDN-21 and the apparent absence of coupled δ 1-κ2 phenotypes in the brain suggest a new approach for targeting receptors.

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