807613-61-2

Upstream product

• 807613-66-7 2-((2S,4S)-2-tert-Butyl-5-oxo-4-phenyl-[1,3]dioxolan-4-yl)-1,4-bis-(4-chloro-phenyl)-butane-1,4-dione 
• 5465-37-2 (E)-1,4-bis(4-chlorophenyl)but-2-ene-1,4-dione 
• 81036-97-7 (2S,5S)-2-tert-butyl-5-phenyl-1,3-dioxolan-4-one 

Relevant academic research and scientific papers

Novel 2-pyrone synthesis via Michael addition of mandelic acid enolate to trans-1,2-diaroylethenes

4-Aroyl-6-aryl-3-phenyl-2-pyrones are synthesized from a mandelic acid dioxolanone. 4-Aroyl-6-aryl-3-phenyl-2-pyrones are prepared in a three-step procedure involving the Michael addition of a cis-2,5-disubstituted-1,3- dioxolan-4-one, derived from mandelic acid, to trans-1,2-diaroylethenes, cyclisation to a furan under acidic conditions and lactonisation. The 2-pyrones can be also obtained directly from the Michael products under prolonged or strong acidic treatment with little decrease in yield.