JNJ 26483327 is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH), an enzyme involved in the breakdown of endocannabinoids in the body. By inhibiting FAAH, JNJ 26483327 increases the levels of endocannabinoids, which are molecules that play a role in regulating various physiological processes, including pain perception, inflammation, and stress. This chemical has shown promise as a potential treatment for chronic pain, inflammatory conditions, anxiety, and other related disorders in preclinical studies. It is being investigated for its therapeutic potential in a range of conditions related to the endocannabinoid system.
807640-87-5
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Basic information
- Product Name: JNJ 26483327
- Synonyms: BGB 102;BGB102;BGB-102;JNJ 26483327;JNJ26483327;JNJ-26483327;17-Bromo-1,8,9,10,11,12,13,14-octahydro-20-methoxy-13-methyl-4,6-ethenopyrimido[4,5-b][6,1,12]benzoxadiazacyclopentadecine;EOS-60486
- CAS NO:807640-87-5
- Molecular Formula: C22H25BrN4O2
- Molecular Weight: 457.3635
- EINECS: N/A
- Product Categories: N/A
- Mol File: 807640-87-5.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 582.4±50.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.310±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 8.26±0.20(Predicted)
- CAS DataBase Reference: JNJ 26483327(CAS DataBase Reference)
- NIST Chemistry Reference: JNJ 26483327(807640-87-5)
- EPA Substance Registry System: JNJ 26483327(807640-87-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 807640-87-5(Hazardous Substances Data)
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807640-87-5 Usage
Uses
Used in Pharmaceutical Industry:JNJ 26483327 is used as a therapeutic agent for the treatment of chronic pain, inflammatory conditions, anxiety, and other related disorders. Its ability to increase endocannabinoid levels makes it a promising candidate for managing these conditions and improving patient outcomes.
Used in Research Applications:
JNJ 26483327 is used as a research tool to study the endocannabinoid system and its role in various physiological processes. This can help scientists better understand the mechanisms underlying pain, inflammation, and stress, and potentially identify new targets for drug development.
Used in Drug Development:
JNJ 26483327 is being investigated for its potential as a lead compound in the development of new drugs targeting the endocannabinoid system. Its selectivity and potency as an FAAH inhibitor make it a valuable starting point for designing more effective and targeted therapies for a range of conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 807640-87-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,0,7,6,4 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.Calculate Digit Verification of CAS Registry Number 807640-87:
(8*8)+(7*0)+(6*7)+(5*6)+(4*4)+(3*0)+(2*8)+(1*7)=175
175 % 10 = 5
So 807640-87-5 is a valid CAS Registry Number.
807640-87-5Upstream product
807640-87-5Downstream Products
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JNJ 26483327
