80765-62-4

Upstream product

• 100-46-9 benzylamine 
• 27382-01-0 1-methyl-4-chloro-1H-pyrrolo<3,2-c>pyridine 
• 80765-61-3 Benzyl-(1-methyl-1H-pyrrolo[3,2-c]pyridin-4-yl)-amine; hydrochloride 

Relevant academic research and scientific papers

4-Substituted-1-methyl-1H-pyrrolopyridines

The synthesis of a series of 4-substituted 1-methyl-1H-pyrrolopyridines is described based on transformations of 4-methyl and 4-chloro analogues.Reactivities of the latter compounds proved less than those of corresponding α-substituted pyridines, but pressure methods allowed isolation of the 4-amino and other amine derivatives in good yield.Under Mannich conditions both 4-methyl and 4-chloro derivatives were converted to bis methanes.

New Heterocyclic Rearrangement: Transformation of 1-Substituted 4-(Alkylamino)-1H-pyrrolopyridines into 1-Substituted 4-(Alkylamino)-1H-pyrrolopyridines (5-Aza- to 7-Azaindoles)

Substitution of 1-alkyl-4-chloro-1H-pyrrolopyridines by primary alkylamines in excess afforded the expected 1-alkyl-4-(alkylamino)-1H-pyrrolopyridines and their 1-alkyl-4-(alkylamino)-1H-pyrrolopyridine isomers resulting from the reve