80772-89-0

Basic information

• Product Name: 2-(β-phenethyl)pyridine N-oxide
• Synonyms: 2-(β-phenethyl)pyridine N-oxide
• CAS NO: 80772-89-0
• Molecular Weight: 199.252
• Mol File: 80772-89-0.mol

Chemical Properties

• CAS DataBase Reference: 2-(β-phenethyl)pyridine N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(β-phenethyl)pyridine N-oxide(80772-89-0)
• EPA Substance Registry System: 2-(β-phenethyl)pyridine N-oxide(80772-89-0)

Safety Data

• Hazardous Substances Data: 80772-89-0(Hazardous Substances Data)

Upstream product

• 14159-54-7 2-(1-phenylethyl)pyridine 
• 110-86-1 pyridine 
• 694-59-7 pyridine N-oxide 
• 4545-21-5 acetophenone p-toluenesulfonylhydrazone 

Downstream Products

• 15260-65-8 2-(1-phenylvinyl)pyridine 
• 80772-84-5 10-methylpyrido[1,2-a]indole 
• 14159-54-7 2-(1-phenylethyl)pyridine 

Relevant articles and documents

Acylation of 2-benzylpyridine N-oxides and subsequent in situ [3,3]-sigamatropic rearrangement reaction

An effective method for the acylation of 2-benzylpyridine N-oxides and their fast in situ [3,3]-sigmatropic rearrangement was reported. This transformation has a wide substrate scope under mild conditions, giving moderate to excellent yields. The application for the synthesis of chiral phenyl-2-pyridylmethanol products was briefly explored. Furthermore, an interesting example of tandem substitution and in situ [3,3]-sigamatropic rearrangement of 2-benzylpyridine N-oxide with benzenecarboximidoyl chloride was reported.

The microwave-assisted ortho-alkylation of azine N-oxides with N-tosylhydrazones catalyzed by copper(i) iodide

A copper catalyzed regioselective cross-coupling of N-tosylhydrazones with azine N-oxides to yield ortho-alkylated products in moderate to good yields is reported. The reaction is facilitated by microwave, takes place without any ligand, and uses inexpensive copper(i) iodide as the catalyst.