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10-(2,3,4,5-Tetramethoxy-6-methyl-phenyl)-deca-2,5-diyn-1-ol is a complex organic compound characterized by a unique molecular structure. It features a deca-2,5-diyn-1-ol backbone, which is a 10-carbon chain with triple bonds at the 2nd and 5th positions, and a hydroxyl group at the 1st position. The phenyl ring is attached at the 10th carbon and is substituted with a methyl group at the 6th position and four methoxy groups at the 2nd, 3rd, 4th, and 5th positions. 10-(2,3,4,5-Tetramethoxy-6-methyl-phenyl)-deca-2,5-diyn-1-ol is known for its potential applications in the synthesis of various pharmaceuticals and chemical intermediates, particularly those with antioxidant properties. Its specific structure and functional groups make it a subject of interest in organic chemistry and medicinal chemistry research.

80810-21-5

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80810-21-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 80810-21-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,8,1 and 0 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 80810-21:
(7*8)+(6*0)+(5*8)+(4*1)+(3*0)+(2*2)+(1*1)=105
105 % 10 = 5
So 80810-21-5 is a valid CAS Registry Number.

80810-21-5Relevant academic research and scientific papers

Quinones. Part 3. Synthesis of Quinone Derivatives having Ethylenic and Acetylenic Bonds: Specific Inhibitors of the Formation of Leukotrienes and 5-Hydroxyicosa-6,8,11,14-tetraenoic Acid (5-HETE)

Shiraishi, Mitsuru,Terao, Shinji

, p. 1591 - 1599 (2007/10/02)

A new series of quinone derivatives with alkenyl and alkynyl groups in the side chain has been synthesised.A ready and novel synthetic method for the preparation of quinone derivatives via application of a 4-hydroxybutylation reaction discovered in our laboratory has been developed.Oxidative demethylation of the hydroquinone dimethyl ethers (5), (9), and (10) with cerium(IV) ammonium nitrate selectively leads to the formation of the desired quinone derivatives (11)-(13) in good yield, in spite of the presence of double or triple bonds, hydroxy groups in the side chains, and/or four methoxy groups on the same phenyl ring.Inhibitory effects of these quinone derivatives on the formation of leukotrienes 4, LTD4, LTB4, and (5S,12S)- and (5S,12R)-6-trans-LTB4> and 5-hydroxyicosa-6,8,11,14-tetraenoic acid (5-HETE) in rat basophilic leukaemia (RBL-1) cells were evaluated.It was found that quinone derivatives such as 2-(12-hydroxydodeca-5,10-diynyl)-3,5,6-trimethyl-1,4-benzoquinone (AA-861) (12d) proved to be potent and specific inhibitors of leukotrienes and 5-HETE formation from arachidonic acid.

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