808109-40-2

Upstream product

• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 808109-75-3 Acetic acid (2S,3S,4S,5R,6S)-3,5-diacetoxy-2-acetoxymethyl-6-allyl-tetrahydro-pyran-4-yl ester 
• 808109-76-4 Toluene-4-sulfonic acid (4aS,6S,7S,8R,8aR)-6-allyl-8-hydroxy-2-(4-methoxy-phenyl)-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester 
• 808109-38-8 (4aS,6S,7S,8S,8aR)-6-Allyl-2-(4-methoxy-phenyl)-hexahydro-pyrano[3,2-d][1,3]dioxine-7,8-diol 
• 808109-77-5 (1aS,2S,3aS,7aS,7bS)-2-Allyl-6-(4-methoxy-phenyl)-hexahydro-1,3,5,7-tetraoxa-cyclopropa[a]naphthalene 
• 477845-03-7 (2S,3S,4S,5R,6S)-2-Allyl-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol 
• 188783-40-6 α/β‐L‐glucopyranosyl‐1,2,3,4,5‐pentaacetate 
• 808109-39-9 (4aS,6S,7R,8R,8aR)-6-Allyl-2-(4-methoxy-phenyl)-8-methyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol 

Downstream Products

• 808109-81-1 2-[(2S,3R,4R,5S,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-3-(4-methoxy-benzyloxy)-4-methyl-tetrahydro-pyran-2-yl]-ethanol 
• 808109-80-0 [(2S,3R,4R,5S,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-3-(4-methoxy-benzyloxy)-4-methyl-tetrahydro-pyran-2-yl]-methanol 
• 808109-43-5 (2S,3S,4R,5R,6S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-5-(4-methoxy-benzyloxy)-4-methyl-6-vinyl-tetrahydro-pyran 
• 808109-44-6 [(2S,3R,4R,5S,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-3-(4-methoxy-benzyloxy)-4-methyl-tetrahydro-pyran-2-yl]-acetaldehyde 
• 808109-42-4 7-(tert-butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-(4-methoxy-phenyl)-8-methyl-hexahydro-pyrano[3,2-d][1,3]dioxine 
• 808109-79-7 2-[(4aS,6S,7S,8R,8aR)-7-(tert-Butyl-dimethyl-silanyloxy)-2-(4-methoxy-phenyl)-8-methyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl]-ethanol 
• 808109-41-3 [(4aS,6S,7S,8R,8aR)-6-Allyl-2-(4-methoxy-phenyl)-8-methyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yloxy]-tert-butyl-dimethyl-silane 
• 808109-78-6 (4aS,6S,7S,8S,8aR)-6-Allyl-2-(4-methoxy-phenyl)-8-methyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol 

Relevant academic research and scientific papers

Structurally simplified macrolactone analogues of halichondrin B

Structurally simplified macrolactone analogues of halichondrin B (e.g., 47, IC50 = 0.67 nM) were identified that retain the potent cell growth inhibitory activity of the natural product in vitro. A structurally simplified macrolactone analogue of halichondrin B was identified that retains the potent cell growth inhibitory activity of the natural product in vitro.