80828-07-5Relevant academic research and scientific papers
Design, synthesis and SAR of novel sulfonylurea derivatives for the treatment of Diabetes mellitus in rats
Sroor, Farid M.,Basyouni, Wahid M.,Aly, Hanan F.,Ali, Sanaa A.,Arafa, Azza F.
, p. 195 - 206 (2021/12/01)
Novel series of sulfonylurea analogs were designed, synthesized and fully characterized. The targeted sulfonylurea analogs 3–11, were prepared in a straight forward manner by nucleophilic addition of aryl-sulfonyl hydrazine derivatives 1a–c to alkyl- or a
STRUCTURE AND REACTIVITY OF HYDRAZINE DERIVATIVES: XLIV. SPECIFIC AND NONSPECIFIC EFFECT OF SOLVENTS IN THE REACTION OF ARENESULFONOHYDRAZIDES WITH PHENYL ISOCYANATE
Veselov, V. Ya.,Shat-skaya, V. A.,Zhurilo, A. A.,Grekov, A. P.
, p. 949 - 952 (2007/10/02)
The kinetics of the reaction of arenesulfonohydrazides with phenyl isocyanate in various types of solvents were studied.Quantitative treatment of the effects of the structure of the arenesulfonohydrazides and the medium on the rate of the reaction showed
STRUCTURE AND REACTIVITY OF HYDRAZINE DERIVATIVES. XLIII. REACTION OF ISOCYANATES WITH ARENESULFONOHYDRAZIDES IN THE PRESENCE OF SOME TRANSITION-METAL β-DIKETONATES IN DIOXANE
Grekov, A. P.,Savel'ev, Yu. V.,Veselov, V. Ya.
, p. 2324 - 2331 (2007/10/02)
The kinetics of the reactions of 1-butyl isocyanate and phenyl isocyanate with arenesulfonohydrazides in dioxane at various temperatures with additions of zinc(II) and iron(III) acetylacetonates, which exhibit a catalytic effect, were studied.It was established that intermediate "catalyst-isocyanate" and "catalyst-hydrazide" molecular complexes are formed in the reactions.A quantitative estimate of the catalytic activity of the investigated metal β-diketonates is given.
STRUCTURE AND REACTIVITY OF HYDRAZINE DERIVATIVES. XLII. KINETICS OF THE REACTIONS OF BENZENESULFONOHYDRAZIDE WITH PHENYL ISOCYANATE IN BENEZENE WITH ADDITIONS OF TRANSITION-METAL ACETYLACETONATES
Grekov, A. P.,Veselov, V. Ya.,Savel'ev, Yu. V.
, p. 1131 - 1137 (2007/10/02)
The kinetics were studied for the reactions of benzenesulfonohydrazide with phenyl isocyanate in benzene at various temperatures in the presence of catalytic amounts of transition-metal (Cr3+, Fe3+, Co3+, Co2+,
STRUCTURE AND REACTIVITY OF HYDRAZINE DERIVATIVES. XLI. REACTION OF BENZENESULFONOHYDRAZIDE WITH PHENYL ISOCYANATE IN MIXTURES OF DIOXANE AND WATER
Grekov, A. P.,Veselov, V. Ya.,Kachorovskaya, O. P.
, p. 961 - 965 (2007/10/02)
The kinetics of the reaction of benzenesulfonohydrazide with phenyl isocyanate in mixtures of dioxane and water were investigated.The reaction rate is determined by the effect of nonspecific solvation of the reagents and by the characteristics of the ther
N-(Phenylsulfonyl)- and N-Methyl-N-(phenylsulfonyl)benzohydrazonyl Azides. Thermally Induced Cyclization to Tetrazoles and Decomposition to Benzonitriles
Ito, Suketaka,Tanaka, Yumo,Kakehi, Akikazu
, p. 539 - 543 (2007/10/02)
N-(phenylsulfonyl)- and N-methyl-N-(phenylsulfonyl)benzohydrazonoyl azides, prepared from the corresponding hydrazonoyl chlorides and sodium azide, undergo the cyclization to 5-phenyl-1-(1-phenylsulfonylamino)-1H-tetrazoles together with the competitive decomposition to benzonitriles and the Curtius-type rearrangement leading to semicarbazides when heated in benzene under reflux.The tetrazole formation of hydrazonoyl azides may be characteristic od such hydrazonoyl azides as those carrying an N-sulfonyl substituent, the strong electron-withdrawing nature of which probably promotes the cyclization.
