80830-88-2Relevant academic research and scientific papers
Elemental Sulfur/DMSO-Promoted Multicomponent One-pot Synthesis of Malonic Acid Derivatives from Maleic Anhydride and Amines
Nguyen, Le Anh,Retailleau, Pascal,Nguyen, Thanh Binh
supporting information, p. 2864 - 2869 (2019/05/01)
Malonic acid derivatives could be conveniently prepared with high degree of functional flexibility via redox condensation reactions between anhydride maleic, amines, elemental sulfur and DMSO as oxidant. This multicomponent decarboxylative transformation consists in a cascade of ring opening, decarboxylative oxidative thioamidation at temperature as low as 50 °C. (Figure presented.).
UNSATURATED THIOLATES IN CYCLOADDITION REACTIONS. IX.* REACTION OF POTASSIUM 1-PIPERIDINO-2-H(ALKYL,ARYL)-ETHENETHIOLATES WITH PHENYL ISOTHIOCYANATE AND PHENYL ISOCYANATE
Bobylev, V. A.,Petrov, M. L.,Petrov, A. A.
, p. 2039 - 2043 (2007/10/02)
Potassium 1-piperidino-2-H(alkyl,aryl)ethenethiolates react with phenyl isothiocyanate and phenyl isocyanate, forming 2-H(alkyl,aryl)-N,N-pentamethylene-N'-phenyldiamides of dithiomalonic and thiomalonic acids respectively.In the reaction of potassium 1-piperidino-2-phenylethenethiolate with phenyl isothiocyanate 5-piperidino-4-phenyl-3-phenylimino-1,2-dithiole is also formed.This compound and also 4-H(alkyl)-5-piperidino-3-phenylimino-1,2-dithioles were obtained by oxidation of substituted amides of dithiomalonic acid described above in the presence of triethylamine.Cyclohexylcarbodiimide does not react with potassium 1-piperidino-2-phenylethenethiolate.
