80834-58-8 Usage
Synonym
PNU-154091
Chemical Class
Quinolinone derivative
Molecular Weight
384.47 g/mol
Structure
The compound consists of a quinolinone ring system with a 3,4-dihydro structure and a 1-butenyl tail with a 4-(4-phenyl-1-piperazinyl) group attached to the 6-position of the ring.
Target Receptor
Dopamine D2 receptor
Mechanism of Action
Selective agonist for the dopamine D2 receptor
Therapeutic Potential
Potential use in the treatment of schizophrenia and other psychiatric disorders
Preclinical Results
Exhibited antipsychotic and antihyperalgesic effects without producing motor side effects commonly associated with traditional antipsychotic medications.
Ongoing Research
Further research is needed to determine the full therapeutic potential of PNU-154091 and its possible applications in the treatment of neurological and psychiatric disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 80834-58-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,8,3 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 80834-58:
(7*8)+(6*0)+(5*8)+(4*3)+(3*4)+(2*5)+(1*8)=138
138 % 10 = 8
So 80834-58-8 is a valid CAS Registry Number.
InChI:InChI=1/C23H27N3O/c27-23-12-10-20-18-19(9-11-22(20)24-23)6-4-5-13-25-14-16-26(17-15-25)21-7-2-1-3-8-21/h1-4,6-9,11,18H,5,10,12-17H2,(H,24,27)/b6-4+
80834-58-8Relevant academic research and scientific papers
Carbostyril derivatives and pharmaceutical composition containing the same
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, (2008/06/13)
Novel carbostyril derivatives and their salts, having antihistaminic effect and central nervous system controlling effect, are represented by the general formula (1), STR1 wherein R1 is a hydrogen atom, a lower alkyl group, a phenyl-lower alkyl
