80854-22-4

Usage

Explanation

This is the chemical name of the compound, which is also known as fenoprofen.

Explanation

Fenoprofen belongs to a class of drugs called NSAIDs, which are commonly used to alleviate pain and reduce inflammation.

Explanation

Fenoprofen works by inhibiting the production of certain substances in the body that cause pain and inflammation, such as prostaglandins.

Explanation

This chemical is frequently used to treat various conditions related to joint and muscle pain, inflammation, and stiffness.

Explanation

Although fenoprofen is effective in alleviating pain and reducing inflammation, it may also cause some side effects that can affect the stomach, blood, and kidneys.

Classification

Nonsteroidal anti-inflammatory drug (NSAID)

Function

Inhibits production of pain-causing substances

Common uses

Treatment of rheumatoid arthritis, osteoarthritis, and musculoskeletal disorders

Side effects

Potential stomach ulcers, bleeding, and kidney problems

Upstream product

• 66202-88-8 methyl 2-(3',4'-dichlorophenyl)-2-methylpropionate 

Downstream Products

• 1040860-96-5 2-(3,4-dichlorophenyl)-2-methylpropanoyl chloride 

Relevant academic research and scientific papers

Palladium-Catalyzed Distal m-C-H Functionalization of Arylacetic Acid Derivatives

Herein, we present m-C-H olefination on derivatives of phenylacetic acids by tethering with a simple nitrile-based template through palladium catalysis. Notably, the versatility of the method is evaluated with a wide range of phenylacetic acid derivatives for obtaining the meta-olefination products in fair to excellent yields with outstanding selectivities under mild conditions. Significantly, the present strategy is successfully exemplified for the synthesis of drugs/natural product analogues (naproxen, ibuprofen, paracetamol, and cholesterol).

Palladium(II)-catalyzed directed trifluoromethylthiolation of unactivated C(sp3)-H bonds

The synthesis of trifluoromethylthiolated aliphatic acid derivatives by Pd-catalyzed C(sp3)-H bond functionalization was developed. Using a bidentate directing group, the direct and selective introduction of a SCF3 moiety was possible on a range of amides with remarkable selectivity for C(sp3)-centers with an electrophilic SCF3 source and pivalic acid as an additive. This work constitutes an example of the unactivated C(sp3)-SCF3 bond formation by C-H activation offering a new access to relevant molecules.

NAPHTHALENONE COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF

Compounds of Formula (I) and Formula (II) are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula(I) and Formula (II) have the following structures, where the definitions of the variables are provided herein.

Pyridylthio-acylanilide herbicides

Novel herbicidally active pyridylthio-acylanilides of the formula STR1 in which R1, R2 and R3, independently of one another, represent hydrogen, halogen, cyano or trifluoromethyl or alkyl, alkoxy and alkylthio having 1 to 4 carbon atoms in each case, R4 represents halogen, methyl or methoxy, n represents a number 0, 1 or 2, z represents the group (Ia) STR2 or the group (Ib) STR3 where X represents oxygen, sulphur, an N--R10 or N--O--R11 group, or X and Rg tpgether represent the STR4 radical, and the other radicals can have various meanings. Intermediates of the formulae STR5 are also new.