808580-45-2Relevant academic research and scientific papers
Indole- and indolizine-glyoxylamides displaying cytotoxicity against multidrug resistant cancer cell lines
James, David A.,Koya, Keizo,Li, Hao,Liang, Guiqing,Xia, Zhiqiang,Ying, Weiwen,Wu, Yaming,Sun, Lijun
, p. 1784 - 1787 (2008/09/19)
We report herein the SAR studies of a series of indole- and indolizine-glyoxylamides that demonstrate substantial in vitro anti-proliferative activities against cancer cell lines, including multidrug resistance (MDR) phenotypes. The in vitro cytotoxic effects have been demonstrated across a wide array of tumor types of various origins (e.g., breast, colon, uterine).
