80866-24-6Relevant academic research and scientific papers
Continuous Visible-Light Photoflow Approach for a Manganese-Catalyzed (Het)Arene C?H Arylation
Liang, Yu-Feng,Steinbock, Ralf,Yang, Long,Ackermann, Lutz
supporting information, p. 10625 - 10629 (2018/08/01)
Manganese photocatalysts enabled versatile room-temperature C?H arylation reactions by means of continuous visible-light photoflow, thus allowing for efficient C?H arylations in 30 minutes with ample scope. The robustness of the manganese-catalyzed photoflow strategy was shown by visible light-induced gram-scale synthesis, clearly outperforming the batch performance.
Synthesis of 2-substituted furans by iron- and palladium-catalyzed coupling reactions
Haner, Jamie,Jack, Kelsey,Nagireddy, Jaipal,Raheem, Mohammed Abdul,Durham, Robin,Tam, William
experimental part, p. 731 - 738 (2011/04/24)
The synthesis of 2-substituted furans via palladium- and iron-catalyzed coupling utilizing 2-bromofuran is described. Whereas palladium-catalyzed Suzuki coupling effectively provided the corresponding aryl furans, little or no product was obtained by palladium-catalyzed coupling with various alkyl nucleophiles. Iron-catalyzed coupling proved effective for the synthesis of primary and secondary alkyl furans in modest yields and aryl furans in low yields. Georg Thieme Verlag Stuttgart New York.
Efficient procedure for the preparation of 2-bromofuran and its application in the synthesis of 2-arylfurans
Raheem, Mohammed-Abdul,Nagireddy, Jaipal R.,Durham, Robin,Tam, William
experimental part, p. 2138 - 2146 (2010/08/13)
A simple, straightforward, and scalable procedure for the preparation of 2-bromofuran using N-bromosuccinimide (NBS) in dimethylformamide (DMF) is reported. The described preparation is conducted on a 20 to 50g scale and does not require extractive workup procedures or chromatographic purifications. To illustrate the synthetic applications of 2-bromofuran, palladium-catalyzed Suzuki coupling reactions of the prepared 2-bromofuran with various aryl boronic acids were investigated, and moderate to good yields of 2-arylfurans were obtained. Copyright Taylor & Francis Group, LLC.
