808736-81-4

Upstream product

• 740839-73-0 3,3-difluoro-5-phenyl-pent-4-yne-1,2-diol 
• 740839-75-2 (1S,2R)-3-(2,2-Dimethyl-[1,3]dioxolan-4-yl)-3,3-difluoro-1-phenyl-propane-1,2-diol 
• 536-74-3 phenylacetylene 
• 82477-43-8 bromodifluoromethylphenylacetylene 
• 740839-76-3 (4R,5S)-4-[((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-difluoro-methyl]-2,2-dimethyl-5-phenyl-[1,3]dioxolane 
• 740839-74-1 4-((E)-1,1-Difluoro-3-phenyl-allyl)-2,2-dimethyl-[1,3]dioxolane 

Downstream Products

• 740839-81-0 Acetic acid (1R,3R)-3,4-diacetoxy-1-((S)-acetoxy-phenyl-methyl)-2,2-difluoro-butyl ester 

Relevant academic research and scientific papers

A stereodivergent asymmetric approach to difluorinated aldonic acids

A (bromodifluoromethyl)alkyne has been deployed in a stereoselective route to difluorinated aldonic acid analogues, in which a Sharpless asymmetric dihydroxylation reaction and diastereoisomer separation set the stage for phenyl group oxidation.