808740-73-0

Basic information

• Product Name: 3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-isoxazole-5-carbaldehyde
• Synonyms: 3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-isoxazole-5-carbaldehyde
• CAS NO: 808740-73-0
• Molecular Weight: 231.208
• Mol File: 808740-73-0.mol

Chemical Properties

• CAS DataBase Reference: 3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-isoxazole-5-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-isoxazole-5-carbaldehyde(808740-73-0)
• EPA Substance Registry System: 3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-isoxazole-5-carbaldehyde(808740-73-0)

Safety Data

• Hazardous Substances Data: 808740-73-0(Hazardous Substances Data)

Upstream product

• 31127-39-6 2,3-dihydrobenzo[b][1,4]dioxin-6-carbaldoxime 
• 29668-44-8 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde 

Downstream Products

• 1421870-04-3 C₂₇H₃₁ClN₄O₃*ClH 
• 1421869-98-8 C₂₉H₃₆N₄O₃*ClH 
• 1421869-92-2 C₃₄H₃₆F₂N₄O₃*ClH 
• 1421869-86-4 C₂₇H₃₁FN₄O₃*ClH 
• 1421869-80-8 C₂₈H₃₄N₄O₄*ClH 
• 1421869-74-0 C₂₇H₃₁ClN₄O₃*ClH 
• 1421869-68-2 C₂₇H₃₁ClN₄O₃*ClH 
• 1421869-62-6 C₂₇H₃₁FN₄O₃*ClH 
• 1421869-56-8 C₂₇H₃₂N₄O₃*ClH 

Relevant articles and documents

Synthesis and biological evaluation of novel T-type Ca2+ channel blockers

A small molecule library of piperazinylalkylisoxazole derivatives containing about 600 compounds was designed, synthesized and evaluated for blocking effects on T-type Ca2+ channel. Several ligands were identified to possess high inhibitory activity against the T-type Ca 2+ channel. The compound 21 with trifluoromethyl substituents at C3-position of phenyl group (R1) and C2- position of phenyl group (R2) showed the highest inhibitory activity with IC50 value of 1.02μM, which is comparable to that of mibefradil.