808748-89-2Relevant articles and documents
Synthesis of C2-C3′N-linked macrocyclic taxoids. Novel docetaxel analogues with high tubulin activity
Querolle, Olivier,Dubois, Jo?lle,Thoret, Sylviane,Roussi, Fanny,Guéritte, Fran?oise,Guénard, Daniel
, p. 5937 - 5944 (2007/10/03)
Novel C2-C3′N-linked macrocyclic taxoids 4 bearing an aromatic ring at position C2 were synthesized. These compounds, tethered between N3′ and the C2-aromatic ring at the ortho, meta, or para position, were constructed by ring-closing metathesis. The para