80879-18-1Relevant academic research and scientific papers
Studies on the Pinacol Coupling Reaction
Mundy, Bradford P.,Srinivasa, Ramanujan,Kim, Youseung,Dolph, Thomas,Warnet, Ronald J.
, p. 1657 - 1661 (2007/10/02)
The mixed pinacol coupling reaction has been carefully analyzed.Although a trend toward statistical distribution of products can be found, it is observed that true statistical distributions are rarely observed.Ring-size and alkyl substituent effects are examined.A through-space heteroatom influence on coupling is noted.By use of (R)-(+)-3-methylcyclohexanone, a very specific effect of coupling conditions on product stereochemistry is observed.
