80879-86-3

Usage

Uses

Used in Dye Production:
2,3-DIMETHYL-4-NITROANILINE is used as a key intermediate in the production of a variety of dyes, including acid, azo, and direct dyes. Its chemical structure allows for the creation of diverse colorants used across different industries.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 2,3-DIMETHYL-4-NITROANILINE serves as an intermediate in the synthesis of various medicinal compounds. Its reactivity and functional groups make it a valuable component in developing new drugs.
Used in Agrochemical Production:
Similarly, in agrochemicals, 2,3-DIMETHYL-4-NITROANILINE is utilized as an intermediate for the synthesis of different agricultural chemicals, contributing to the development of products that enhance crop protection and yield.
Safety Precautions:
Given its toxic nature, 2,3-DIMETHYL-4-NITROANILINE can cause irritation to the skin, eyes, and respiratory system. Therefore, it is crucial to handle and use 2,3-DIMETHYL-4-NITROANILINE with appropriate safety measures to prevent adverse health effects.

InChI:InChI=1S/C8H10N2O2/c1-5-6(2)8(10(11)12)4-3-7(5)9/h3-4H,9H2,1-2H3

Upstream product

• 114166-32-4 2,3-dimethyl-4-nitroacetanilide 
• 7664-93-9 sulfuric acid 
• 87-59-2 2,3-Dimethylaniline 
• 134-98-5 N-(2,3-dimethylphenyl)acetamide 
• 138330-47-9 2,3-dimethyl-6-nitroacetanilide 

Downstream Products

• 285124-10-9 2,3-dimethyl-4-nitrophenyl isothiocyanate 
• 5628-44-4 amyldimethyl-para-aminobenzoic acid 
• 5628-45-5 4-Amino-2,3-dimethyl-benzoesaeure-methylester 
• 5628-61-5 4-methoxy-2,3-dimethyl-benzoic acid 
• 5628-62-6 4-Methoxy-2,3-dimethyl-benzoesaeure-methylester 
• 6021-31-4 4-hydroxy-2,3-dimethylbenzoic acid 
• 5628-56-8 methyl 2,3-dimethyl-4-hydroxybenzene-1-carboxylate 
• 90564-15-1 4-Nitro-2,3-dimethyl-benzoesaeure 
• 90922-70-6 4-Nitro-2,3-dimethyl-benzoesaeure-methylester 
• 90557-85-0 4-Nitro-2,3-dimethyl-benzamid 
• 74319-86-1 4-amino-2,3-dimethylbenzenesulfonic acid 
• 343947-14-8 2,3-Dimethyl-4-nitro-benzenesulfonyl chloride 
• 114166-32-4 2,3-dimethyl-4-nitroacetanilide 
• 101421-63-0 1-bromo-2,3-dimethyl-4-nitro-benzene 

Relevant academic research and scientific papers

Design and synthesis of urea-linked aromatic oligomers-a route towards convoluted foldamers

Herein we report the design and synthesis of crescent-shaped and helical urea-based foldamers, the curvature of which is controlled by varying the constituent building blocks and their connectivity. These oligomers are comprised of two, three or five alternating aromatic heterocycles (pyridazine, pyrimidine or pyrazine) and methyl-substituted aromatic carbocycles (tolyl, o-xylyl or m-xylyl) connected together through urea linkages. A crescent-shaped conformational preference is encoded within these π-conjugated urea-linked oligomers based on intramolecular hydrogen bonding and steric interactions; the degree of curvature is tuned by the urea connectivity to the heterocycles and the aryl groups. NMR characterization of these foldamers confirms the intramolecular hydrogen-bonded conformation expected (Z,E configuration of the urea bond) in both the pyridazyl and pyrimidyl foldamers in solution. An X-ray crystal structure of the N3,N6-diisobutylpyridazine-4,6- diamine-o-tolyl urea-linked foldamer (4) confirms the presence of N-H...N hydrogen bonds between the heterocyclic nitrogen atom and the free hydrogen of the urea linkage. Additionally, the tolyl methyl group interacts unfavourably with the urea carbonyl oxygen, thus destabilising the alternate planar conformation.

One-pot reaction as an efficient method for rigid molecular tweezers

(Equation Presented) Rigid molecular tweezers are compounds of increasing scientific interest. As the structural requirements for such compounds are highly specific, few types of these tweezers are thus far known. The preparation of examples of rigid larg

Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents

This invention relates to 2-arylimino heterocycles, including 2-arylimino-1,3-thiazolidines, 2-arylimino-2,3,4,5-tetrahydro-1,3-thiazines, 2-arylimino-1,3-thiazolidin-4-ones, 2-arylimino-1,3-thiazolidin-5-ones, and 2-arylimino-1,3-oxazolidines, and their use in modulating progesterone receptor mediated processes, and pharmaceutical compositions for use in such therapies.

Studies of Reactions of Amines with Sulfur Trioxide. VI. Thermal Reactions of Anilinium, Dimethylanilinium, and Trimethylanilinium Salts of Butylamidosulfuric Acid

When the title compounds were heated in an evacuated reaction vessel, both transsulfonation and rearrangement occurred.At lower temperatures (80-120 deg C) the corresponding phenylamidosulfates and sulfophenylamidosulfates (transsulfonation products) were the main products.Increasing temperature led to the formation of ring mono- and disulfonates (rearrangement products) at the expense of the transsulfonation products.The sulfonate group always migrated to the ortho and/or para position(s) to the amino group.In no case was any meta-product detected.There was no significant difference in the ease of transsulfonation among the anilinium salts studied exept 2,6-dimethyl- and 2,4,6-trimethylanilinium salts.On the other hand, the ease of rearrangement and the orientation of ring sulfonation depended strongly on the structure of the substrate anilines.The thermal reactions of 2,4,6-trimethylanilinium butylamidosulfate produced (2,4,6-trimethylphenylimido)bis(sulfate) in addition to (2,4,6-trimethylphenylamido)sulfate.This is the first isolation of an arylimidobis(sulfate) from such reactions.Mechanisms of the transsulfonation and rearrangement have been discussed.