80900-48-7

Upstream product

• 2785-98-0 2,5-dimethoxybenzoic acid 

Downstream Products

• 73177-39-6 1-(3,5-Dimethoxy-benzyl)-2,5-dimethoxy-cyclohexa-2,5-dienecarboxylic acid 
• 73177-40-9 2,5-Dimethoxy-1-(4-methoxy-benzyl)-cyclohexa-2,5-dienecarboxylic acid 
• 80900-49-8 (3',3'-ethylenedioxypentyl)-2,5-dimethoxy-2,5-cyclohexadiene-1-carboxylic acid 
• 73177-43-2 2,5-Dimethoxy-1-<(3'-methoxy-2'-(methoxycarbonyl)phenyl)methyl>-2,5-cyclohexadiene-1-carboxylic acid 
• 73177-38-5 2,5-Dimethoxy-1-(3-methoxy-benzyl)-cyclohexa-2,5-dienecarboxylic acid 
• 73177-42-1 2,5-Dimethoxy-1-(2-methyl-benzyl)-cyclohexa-2,5-dienecarboxylic acid 
• 73177-41-0 1-Benzyl-2,5-dimethoxy-cyclohexa-2,5-dienecarboxylic acid 

Relevant academic research and scientific papers

Studies on Gibberellin Synthesis: The Total Synthesis of Gibberellic Acid from Hydrofluorenone Intermediates

Reductive alkylation of 2,5-dimethoxybenzoic acid with benzyl iodide 15 followed by cyclodehydration furnished fluorenone 8 which was converted into gibbane 10 by means of an acid-catalyzed intramolecular cyclization procedure based on diazo ketone 21.Ben

Reductive Alkylation of 2,5-Dimethoxybenzoic Acid: A Direct Synthesis of Dihydrofluoren-2-ones

A two-operation procedure is described for the synthesis of 3,4-dihydrofluoren-2(1H)-ones from "reductive alkylation" of 2,5-dimethoxybenzoic acid with benzyl halides, followed by cyclodehydration of the adducts, with concomitant decarboxylation.