809277-06-3Relevant academic research and scientific papers
Synthesis and biological evaluation of 5R- and 5S-methyl substituted D- and L-configuration 1,3-dioxolane nucleoside analogs
Bera, Sanjib,Malik, Leila,Bhat, Balkrishen,Carroll, Steven S.,Hrin, Renee,MacCoss, Malcolm,McMasters, Daniel R.,Miller, Michael D.,Moyer, Greg,Olsen, David B.,Schleif, William A.,Tomassini, Joanne E.,Eldrup, Anne B.
, p. 6237 - 6247 (2004)
1,3-Dioxolane and 1,3-oxathiolane nucleoside analogs play an important role in anti-viral and anti-neoplastic chemotherapy. We report here the synthesis of 2-hydroxymethyl-5-methyl-1,3-dioxolanylpurine nucleosides from 4-acetoxy-2-(benzyloxymethyl)-5-meth
