809285-62-9

Upstream product

• 809285-87-8 C₆₀H₇₂N₂O₁₃ 
• 809285-77-6 C₆₁H₇₄N₂O₁₃ 
• 809285-76-5 2-[(2R,10S,12S)-10-{2-[(2R)-4-iodo-2-methoxybut-3-enyl]oxazol-4-oyloxy}-2-methoxy-12-(4-methoxybenzyloxy)-11,11-dimethylpentadeca-3,7,13-trien-5-ynyl]-oxazole-4-carboxylic acid methyl ester 
• 809285-75-4 2-{(2R,10S,12S)-[10-hydroxy-2-methoxy-12-(4-methoxybenzyloxy)-11,11-dimethylpentadeca-3,7,13-trien-5-ynyl]}-oxazole-4-carboxylic acid methyl ester 
• 809285-69-6 (3Z,6S,8S,9E)-8-(4-methoxybenzyloxy)-7,7-dimethyl-1-(triisopropylsilyl)undeca-3,9-dien-1-yn-6-ol 

Relevant academic research and scientific papers

Self-Assembly of Disorazole C1 through a One-Pot Alkyne Metathesis Homodimerization Strategy

Abstract Alkyne metathesis is increasingly explored as a reliable method to close macrocyclic rings, but there are no prior examples of an alkyne-metathesis-based homodimerization approach to natural products. In this approach to the cytotoxic C2-symmetric marine-derived bis(lactone) disorazole C1, a highly convergent, modular strategy is employed featuring cyclization through an ambitious one-pot alkyne cross-metathesis/ring-closing metathesis self-assembly process.