809288-09-3

Basic information

• Product Name: 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 2,2,2-trifluoroacetate
• Synonyms: 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 2,2,2-trifluoroacetate
• CAS NO: 809288-09-3
• Molecular Formula: C8H10F3NO3
• Molecular Weight: 225.1651096
• Mol File: 809288-09-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 2,2,2-trifluoroacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 2,2,2-trifluoroacetate(809288-09-3)
• EPA Substance Registry System: 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 2,2,2-trifluoroacetate(809288-09-3)

Safety Data

• Hazardous Substances Data: 809288-09-3(Hazardous Substances Data)

Upstream product

• 76-05-1 trifluoroacetic acid 

Relevant articles and documents

Hetero-Diels-Alder reaction of phosphinyl and phosphonyl nitroso alkenes with conjugated dienes: An aza-Cope rearrangement

Phosphorylated nitroso alkenes react with cyclic dienes such as cyclopentadiene or cyclohexadiene to afford hetero Diels-Alder-type cycloadducts where the nitroso alkene participates as dienophile component and the cyclic olefin acts as the 4π-electron (diene) system. Subsequent aza-Cope rearrangement affords highly functionalized 5,6-dihydro-4H-1,2-oxazines. Conversely, the reaction of TMS-substituted cyclopentadiene (dienophile) with nitroso alkenes as heterodienes leads directly to bicyclic 1,2-oxazines. Theoretical studies are in agreement with the experimental results and with the new aza-Cope rearrangement proposed.