80935-73-5Relevant academic research and scientific papers
Ring Opening Reaction of 3,6-Dihydro-2-(1H)pyrimidinones with Hydroxylamine Hydrochloride
Kashima, Choji,Katoh, Akira,Yokota, Yuko,Omote, Yoshimori
, p. 1469 - 1470 (2007/10/02)
1,4,6-Trisubstituted 3,6-dihydro-2-(1H)pyrimidinones (Ia-d) easily underwent the ring opening reaction with hydroxylamine hydrochloride to afford the oximes (IIa-d) in good yields.In the case of 3,6-dihydro-6-methyl-1-phenyl-2-(1H)pyrimidinone (Ie), 2-anilinobutyronitrile (III) was obtained in addition to the oxime (IIe).Dihydro-2-(1H)pyrimidinone (IV) and -thiones (V and VI) did not undergo the ring opening reaction.
