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Usage

Uses

Used in Dye Production:
5-Phenyl-O-toluidine is used as a precursor in the synthesis of dyes, contributing to the coloration of various materials due to its chemical reactivity and ability to form stable dye molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 5-Phenyl-O-toluidine serves as an intermediate in the manufacturing of certain drugs, leveraging its chemical properties to facilitate the development of medicinal compounds.
Used in Industrial Applications:
5-Phenyl-O-toluidine is employed across various industries for its diverse applications, including but not limited to the production of pigments, rubber chemicals, and other specialty chemicals, where its unique properties are harnessed to meet specific industrial needs.

InChI:InChI=1/C13H13N/c1-10-7-8-12(9-13(10)14)11-5-3-2-4-6-11/h2-9H,14H2,1H3

Upstream product

• 80726-54-1 1-methyl-2-nitro-4-phenylbenzene 
• 591-50-4 iodobenzene 
• 66003-76-7 Diphenyliodonium triflate 
• 1146127-24-3 N-(4-methyl-[1,1'-biphenyl]-3-yl)pivalamide 
• 39478-78-9 5-bromo-2-methylaniline 
• 98-80-6 phenylboronic acid 
• 119-32-4 4-Methyl-3-nitroanilin 

Downstream Products

• 99309-17-8 (1S,5R,7S)-1,5,7-Trimethyl-3-(4-methyl-biphenyl-3-yl)-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid 
• 113431-48-4 8-methyl-5-phenylquinoline 
• 113431-49-5 5-phenylquinoline-8-carboxylic acid 
• 113431-38-2 5-Phenyl-quinoline-8-carboxylic acid (2-dimethylamino-ethyl)-amide; hydrochloride 
• 99309-18-9 (1S,5R,7S)-1,5,7-Trimethyl-3-(4-methyl-biphenyl-3-yl)-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carbonyl chloride 
• 672960-76-8 tert-butyl [1-(5-phenyl-2-toluidinylcarbamoyl)-1-phenyl-methyl]-carbamate 
• 1046488-77-0 C₃₃H₃₆N₂O 
• 1126366-26-4 N-(2-methyl-5-phenyl-phenyl)-4-(pyridin-2-ylmethoxy)benzamide 

Relevant academic research and scientific papers

A Modular Flow Design for the meta-Selective C?H Arylation of Anilines

Described herein is an effective and practical modular flow design for the meta-selective C?H arylation of anilines. The design consists of four continuous-flow modules (i.e., diaryliodonium salt synthesis, meta-selective C?H arylation, inline copper extraction, and aniline deprotection) which can be operated either individually or consecutively to provide direct access to meta-arylated anilines. With a total residence time of 1 hour, the desired product could be obtained in high yield and excellent purity without the need for column chromatography, and the residual copper content meets the standards for parenterally administered pharmaceutical substances.

Ligand-Free C–C Coupling Reactions Promoted by Hexagonal Boron Nitride-Supported Palladium(II) Catalyst in Water

A micron-scale palladium(II) material has been successfully prepared using Schiff base-modified hexagonal boron nitride as a support and used for the first time as an efficient and recyclable catalyst in organic synthesis. The morphology, composition, metal loading and thermal stability of the catalyst were studied using scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), infrared spectroscopy (FT-IR), inductively coupled plasma (ICP) and thermogravimetric (TG) analyses. Then, the micron material was tested in various C–C cross-coupling reactions and exhibited excellent catalytic activities in the Suzuki and Heck reactions. Moreover, the catalyst could be easily recovered by simple filtration and reused at least ten times without significant loss of its catalytic activity. In general, this work demonstrates the possibility of using Schiff-base@hexagonal boron nitride as an efficient support for heterogeneous catalysts. (Figure presented.).

Novel cyclodextrin-modified h-BN@Pd(II) nanomaterial: An efficient and recoverable catalyst for ligand-free C-C cross-coupling reactions in water

An environmentally friendly palladium(II) catalyst supported on cyclodextrin-modified h-BN was successfully prepared. The catalyst was characterized by FT-IR, SEM, TG, XRD and XPS, and the loading level of Pd in h-BN@β-CD@Pd(II) was measured to be 0.088?mmol g?1 by ICP. It exhibits excellent catalytic activity for the Suzuki and Heck reactions in water, and can be easily separated and consecutively reused for at least nine times. In addition, a series of pharmacologically interesting products were successfully synthesized using this catalyst to demonstrate its potential applications in pharmaceutical industries. Above all, this work opens up an interesting and attractive avenue for the use of cyclodextrin-functionalized h-BN as an efficient support for hydrophilic heterogeneous catalysts.

NOVEL COMPOUND

A compound is represented by the following formula (1). In the formula (1), Ar is a substituted or unsubstituted aryl group including 6 to 30 ring carbon atoms, Ra are independently a substituted or unsubstituted alkyl group including 1 to 15 c

Palladium(II)-Schiff base complex immobilized covalently on h-BN: An efficient and recyclable catalyst for aqueous organic transformations

A moisture- and air-stable palladium(II)-Schiff base complex supported on h-BN was simply prepared by using commercially available reagents. This nanomaterial was applied as an excellent and recyclable heterogeneous catalyst for the Suzuki and Heck cross-coupling reactions. And it has been characterized by FT-IR, XRD, SEM, XPS, TG and ICP-AES techniques. High yields, ligand-free, low reaction time, water as solvent, non-toxicity and recyclability of the catalyst are the main merits of these protocols. In addition, a series of pharmacologically relevant products were successfully synthesized using this catalyst. Above all, this work opens up an interesting and attractive avenue for the use of h-BN as an efficient support for heterogeneous catalysts.