80971-68-2Relevant academic research and scientific papers
UREA DERIVATIVES AS PYRUVATE KINASE ACTIVATORS
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, (2022/02/15)
The subject matter described herein is directed to pyruvate kinase activating compounds of Formula I and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds and methods of administering the compounds for the treatment of diseases associated with PKR and/or PKM2, such as pyruvate kinase deficiency, sickle cell disease, and beta-thalassemia.
Peptide Synthesis with 1-Aminocyclopropane-1-carboxylic Acid
Stewart, Frederick H. C.
, p. 2431 - 2438 (2007/10/02)
Peptide derivatives of 1-aminocyclopropane-1-carboxylic acid have been synthesized by model active ester coupling reactions in order to compare the steric effect of this plant amino acid with that of its open-chain congener 2-methylalanine.An analogue of
