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Upstream product

• 3535-37-3 3,4-dimethoxybenzoic acid chloride 
• 1657006-78-4 C₂₀H₁₈Br₂Cl₂O₄ 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 126267-46-7 3',5'-dichloro-2'-hydroxy-3,4-dimethoxy-trans-chalcone 
• 3321-92-4 1-(3,5-dichloro-2-hydroxyphenyl)-ethanone 

Relevant academic research and scientific papers

Iodine catalyzed cascade synthesis of flavone derivatives from 2'-allyloxy-α,β-dibromochalcones

Synthesis of flavones from 2'-allyloxy-α, β-dibromochalcones has been described. The iodine induced oxidative cyclization of 2'-allyloxy-α, β-dibromochalcones results into the formation of 3-bromoflavanones which ultimately gives flavones. Dehydrobromination of 3-bromoflavanone to give flavone is the preferred reaction over dehydrogenation.

Synthesis and biological activities of some flavones

Chalcones are synthesized by a base catalyzed Claisen Schmidt condensation reaction and then treated with dimethylsulphoxide in presence of iodine to get flavones. The synthesized compounds were evaluated for their antibacterial activity against Escherichia coli, P. aeruginosa, S. epidermidis and B. subtilis. All the flavones showed moderate to good activity. The structures of these compounds were confirmed by IR, UV, 1H NMR, Mass and elemental analysis.

Synthesis and biological activities of some flavones

Chalcones are synthesized by a base catalyzed Claisen Schmidt condensation reaction and then treated with dimethylsulphoxide in presence of iodine to get flavones. The synthesized compounds were evaluated for their antibacterial activity against Escherichia coilt P. aeruginosa, S. epidermidis and B. subtilis. All the flavones showed moderate to good activity. The structures of these compounds were confirmed by IR, UV, 1H NMR, Mass and elemental analysis.

Synthetic Flavonoids and Pharmaceutical Compositions and Therapeutic Methods of Treatment of HIV infection and other pathologies

A compound, pharmaceutical composition and method for the treatment of mammals wherein the active therapeutic agent is a compound having the structure: wherein: R1 is an electronegative substituent, R2 is R1 or alkyl,R3 is H or O-alkyl,R4 and R5 are the same or different and are alkyl andR6 is H or OH.

Synthesis of chromones and pyrazolines as antimicrobial & antifungal agents

A series of chromones and pyrazolines have been synthesized and evaluated for their antimicrobial and antifungal activity against Gram+ve and Gram-ve microorganisms. 2-Hydroxy acetophenone on treatment with substituted aldehydes gave the corresponding cha

Synthetic Flavonoids and Pharmaceutical Compositions and Therapeutic Methods of Treatment of Cancer and other Pathologies

A compound, pharmaceutical composition and method for the treatment of mammals wherein the active therapeutic agent is a compound having the structure: wherein: R1 is an electronegative substituent,R2 is R1 or alkyl,R

Synthesis of novel substituted flavonoids

Eighteen substituted chalcones, flavones and 3-flavonols were synthesized and characterized using 1H-NMR, IR and elemental analysis. The substitution pattern includes two halogen atoms, nitro and methyl groups in ring A as well as two or three