81-55-0 Usage
Chemical Properties
brownish-gold solid
Uses
1,8-Dihydroxy-4,5-dinitro-9,10-anthracenedione is a NS2B-NS3 protease specific inhibitor that is used for treatment of Dengue and West Nile virus infections.
General Description
Brownish gold solid.
Air & Water Reactions
The neat (pure) material is sensitive to air and may be sensitive to light. . Insoluble in water.
Reactivity Profile
A nitrated alcohol and a ketone. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
Fire Hazard
Flash point data for 1,8-Dihydroxy-4,5-dinitroanthraquinone are not available, however, 1,8-Dihydroxy-4,5-dinitroanthraquinone is probably combustible.
Check Digit Verification of cas no
The CAS Registry Mumber 81-55-0 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 1 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 81-55:
(4*8)+(3*1)+(2*5)+(1*5)=50
50 % 10 = 0
So 81-55-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H6N2O8/c17-7-3-1-5(15(21)22)9-11(7)14(20)12-8(18)4-2-6(16(23)24)10(12)13(9)19/h1-4,17-18H
81-55-0Relevant articles and documents
An improved practical synthesis of leuco-1,4,5,8-tetrahydroxyanthraquinone
Chang,Cheng
, p. 1893 - 1900 (2007/10/02)
Leuco-1,4,5,8-tetrahydroxyanthraquinone was prepared from chrysazin by nitration and reduction with iron powder, followed by treatment with sodium hydrosulfite in alkaline solution. This method is suitable for scaling, and is significant and improved over literature methods.
