81033-30-9Relevant academic research and scientific papers
Regioselective synthesis and side-chain metallation and elaboration of 3-aryl-5-alkylisoxazoles
Di Nunno, Leonardo,Scilimati, Antonio,Vitale, Paola
, p. 2659 - 2665 (2007/10/03)
A number of 3-aryl-5-alkylisoxazoles have been synthesized in high yields by reacting arylnitrile oxides with free enolate ions regioselectively obtained by metallation of various alkyl methyl ketones with LDA in THF at -78°C followed by dehydration. Inve
HYDRATION AND HYDROGENATION OF ACETYLENIC SIDE-CHAINS AT THE 4- OR 5-POSITION OF ISOXAZOLES
Yamanaka, Hiroshi,Shiraiwa, Masafumi,Sakamoto, Takao,Konno, Shoetsu
, p. 3548 - 3553 (2007/10/02)
Hydration of 5-isoxazolyl-phenyl(or -butyl)acetylenes (1a, b) in dilute sulfuric acid in the presence of mercuric sulfate afforded 5-isoxazolylmethyl phenyl (or butyl) ketones (3a, b), predominantly.In contrast, the hydration of 4-isoxazolyl-phenyl(or -bu
