81036-84-2

Usage

Uses

Used in Pharmaceutical Industry:
1-Bromo-5-dioxolanecyclohex-1-ene is used as a key intermediate for the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 1-Bromo-5-dioxolanecyclohex-1-ene serves as an essential building block for the production of agrochemicals, such as pesticides and herbicides, contributing to the development of more effective and environmentally friendly products.
Used in Fine Chemicals Industry:
1-Bromo-5-dioxolanecyclohex-1-ene is utilized as an intermediate in the synthesis of fine chemicals, including fragrances, dyes, and other specialty chemicals, enhancing the diversity and quality of products in this industry.
Used as a Reagent in Organic Reactions:
1-Bromo-5-dioxolanecyclohex-1-ene is employed as a reagent in various organic reactions, such as nucleophilic substitution and cross-coupling reactions, facilitating the formation of new chemical entities and expanding the scope of organic synthesis.
It is crucial to handle 1-Bromo-5-dioxolanecyclohex-1-ene with care due to its potential hazards if not used properly, ensuring safety in research and industrial applications.

InChI:InChI=1/C8H11BrO2/c9-7-2-1-3-8(6-7)10-4-5-11-8/h2H,1,3-6H2

Upstream product

• 56671-81-9 3-bromo-2-cyclohexen-1-one 
• 107-21-1 ethylene glycol 
• 504-02-9 1,3-cylohexanedione 

Downstream Products

• 66085-04-9 3-(trimethylsilyl)-2-cyclohexen-1-one 
• 81036-92-2 Bicyclohexyl-1-ene-3,3'-dione 
• 81036-89-7 3-(1-hydroxycyclohexane-1-yl)-2-cyclohexen-1-one 
• 81770-73-2 C₈H₁₀⁽²⁾H₂O₂ 
• 81036-87-5 C₈H₁₀⁽²⁾HBrO₂ 
• 81036-91-1 3-(α-hydroxybenzyl)-2-cyclohexen-1-one 
• 17299-34-2 3-ethylcyclohex-2-en-1-one 
• 81036-90-0 3-(1-hydroxycyclopentane-1-yl)-2-cyclohexen-1-one 
• 1193-18-6 3-methylcyclohexen-2-one 
• 1189572-91-5 C₁₆H₂₄O₂ 
• 1189572-90-4 C₁₅H₂₂O₂ 
• 1189572-89-1 C₁₄H₂₀O₂ 
• 1401088-31-0 C₁₃H₂₂O₂Si 
• 1329607-69-3 C₁₆H₁₇BrO₂ 

Relevant academic research and scientific papers

The β-effect of silicon in the orthogonal geometry

The inductive contribution to the β-effect of silicon has been investigated through the preparation of 1-(trimethylsilyl)bicyclo[2.2.2]octan-2-ol (5-OH) and its sulfonate derivatives. The dihedral relationship in 5 between the trimethylsilyl group and the

Use of Protected β-Bromocyclopentenones and β-Bromocyclohexenones as β-Acylvinyl Anion Equivalents

Ethylene glycol ketals of the 3-bromocyclohex-2-en-1-one as well as its 2-methyl, 2-n-propyl, and 5,5-dimethyl derivatives have been prepared, and their reactions with butyllithium were studied.The organolithium reagents derived from the above compounds react with a variety of electrophiles to afford after acid hydrolysis the corresponding 3-substituted cyclohexenones.Attempts to prepare the ethylene glycol ketal of 2-methyl-3-bromocyclopent-2-en-1-one gave a low yield of the bromoketal.However, dithioketals of 3-bromocyclopent-2-en-1-one and its 2-methyl derivativecould be prepared in good yield.The metalation chemistry of the dithioketals in both the five- and six-membered-ring series was examined.The functionalization chemistry of the resulting organolithium compounds afforded after dithioketal hydrolysis 3-functionalized cyclohex-2-en-1-ones and cyclopent-2-en-1-ones.Several limitations of the chemistry using allyl bromide and cyclohexenone as electrophiles are noted.

An Efficient and Simple β-Acylvinyl Anion Equivalent for Cyclohexenones

Dilithio species available from treatment of Δ3,4-3-bromocyclohexenone ketals with two equivalents of n-butyllithium serve as one-pot equivalents of β-vinyl-carbanions of cyclohexenones.These former ketals are available in good yield from the corresponding β-bromocyclohexenone by direct ketalization under controlled conditions.