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4-Hydroxy-4-(methoxycarbonylmethyl) cyclohexane, also known as "1,1-Bis(hydroxymethyl)cyclohexane", is a cyclic chemical compound with the molecular formula C9H16O3. It features a cyclohexane ring with a hydroxyl group and a methoxy group attached, providing unique structural and functional characteristics. 4-Hydroxy-4-(methoxycarbonylmethyl)
cyclohexane is highly valued as a versatile building block and intermediate in the synthesis of a diverse array of organic compounds, including pharmaceuticals, agrochemicals, and flavors.

81053-14-7

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81053-14-7 Usage

Uses

Used in Pharmaceutical Industry:
4-Hydroxy-4-(methoxycarbonylmethyl) cyclohexane is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of new drugs with potential therapeutic applications, contributing to the development of novel treatments for a range of medical conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Hydroxy-4-(methoxycarbonylmethyl) cyclohexane serves as an essential building block for the production of various agrochemicals. Its incorporation into these products can enhance their effectiveness in crop protection and support sustainable agricultural practices.
Used in Flavor and Fragrance Industry:
4-Hydroxy-4-(methoxycarbonylmethyl) cyclohexane is utilized as a starting material in the synthesis of flavors and fragrances. Its unique functional groups enable the creation of new, complex scent profiles, enriching the palette of available fragrances and flavorings for various consumer products.
It is crucial to handle and store 4-Hydroxy-4-(methoxycarbonylmethyl) cyclohexane with care, adhering to proper safety guidelines and regulations to ensure the safe and effective use of this valuable compound in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 81053-14-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,0,5 and 3 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 81053-14:
(7*8)+(6*1)+(5*0)+(4*5)+(3*3)+(2*1)+(1*4)=97
97 % 10 = 7
So 81053-14-7 is a valid CAS Registry Number.

81053-14-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 2-(1-hydroxy-4-oxocyclohexyl)acetate

1.2 Other means of identification

Product number -
Other names W1900

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:81053-14-7 SDS

81053-14-7Downstream Products

81053-14-7Relevant academic research and scientific papers

Isolation and structure–activity relationship studies of jacaranones: Anti-inflammatory quinoids from the Cuban endemic plant Jacaranda arborea (Bignoniaceae)

Hirukawa, Minako,Zhang, Menghua,Echenique-Diaz, Lazaro M.,Mizota, Koji,Ohdachi, Satoshi D.,Begué-Quiala, Gerardo,Delgado-Laba?ino, Jorge L.,Gámez-Díez, Jorgelino,Alvarez-Lemus, José,Machado, Leandro Galano,Nú?ez, Miguel Suárez,Shibata, Takahiro,Kigoshi, Hideo,Kita, Masaki

, (2020)

The Cuban endemic plant Jacaranda arborea (Bignoniaceae) has been traditionally used in folk medicine as an acaricide and for acne treatment. Two known quinoids, methyl (1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)acetate (jacaranone) (1) and its ethyl ester 2 were isolated from this species as anti-inflammatory substances. Compound 1 prominently inhibited the production of TNF-α in both LPS-treated macrophages and mice, with low toxicity. Structure-activity relationship studies revealed that the high electrophilicity of 1 as a Michael acceptor played an important role in these effects. Unlike in previous studies, such as those on antitumor, anti-oxidant, and anti-malarial activities, ester derivatives of 1 retained their potent anti-inflammatory activity. Our results suggest that jacaranones may target specific biomacromolecule(s) at lower concentrations than hitherto expected to exhibit potent activities.

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