81060-32-4

Basic information

• Product Name: Benzamide, N,N-diethyl-2-formyl-4-methoxy-
• CAS NO: 81060-32-4
• Molecular Formula: C13H17NO3
• Molecular Weight: 235.283
• Mol File: 81060-32-4.mol

Chemical Properties

• CAS DataBase Reference: Benzamide, N,N-diethyl-2-formyl-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N,N-diethyl-2-formyl-4-methoxy-(81060-32-4)
• EPA Substance Registry System: Benzamide, N,N-diethyl-2-formyl-4-methoxy-(81060-32-4)

Safety Data

• Hazardous Substances Data: 81060-32-4(Hazardous Substances Data)

Upstream product

• 7465-86-3 4-methoxy-N,N-diethylbenzamide 
• 68-12-2 N,N-dimethyl-formamide 
• 100-09-4 4-methoxybenzoic acid 

Downstream Products

• 113261-61-3 2-(Cyano-trimethylsilanyloxy-methyl)-N,N-diethyl-4-methoxy-benzamide 

Relevant articles and documents

Rational design of inhibitors of VirA-VirG two-component signal transduction

VirA-VirG two-component system regulates the vir (virulence) operon in response to specific host factors (xenognosins) in the plant pathogen Agrobacterium tumefaciens. Using whole cell assays, stable inhibitors inspired by the labile natural benzoxazinone inhibitor HDMBOA are developed. It is found that aromatic aldehydes represent a minimal structural unit for activity. In particular, 3-hydroxy-4,6-dimethoxy-3H-isobenzofuran-1-one (HDI) was found to have the highest activity, making it the most potent developed inhibitor of virulence gene expression in Agrobacterium.

A regioselective synthesis of dimethyl phthalide-3-phosphonates

Dimethyl phthalide-3-phosphonates having various substituents on the benzene ring were regioselectively synthesized by the reaction of N,N-diethyl-2-formylbenzamides with tert-butyldimethylsilyl dimethyl phosphite followed by treatment with methanesulfonic acid. N,N-Diethyl-2-formylbenzamides were regioselectively prepared by ortho lithiation-formylation of the corresponding benzamides.