810629-01-7

Upstream product

• 6642-31-5 6-Amino-1,3-dimethylbarbituric acid 
• 104-88-1 4-chlorobenzaldehyde 
• 126-81-8 dimedone 
• 769-42-6 1,3-dimethylbarbituric acid 
• 873-95-0 1-amino-5,5-dimethylcyclohexen-3-one 

Relevant academic research and scientific papers

Cesium salt of 2-molybdo-10-tungstophosphoric acid as an efficient and reusable catalyst for the synthesis of uracil derivatives: Via a green route

A solid catalyst, cesium salt of 2-molybdo-10-tungstophosphoric acid (Cs2.3H0.7PW10Mo2O40) named as Cs-3, was synthesized by a simple, cheap, clean, and eco-friendly method. The physicochemical properties of the synthesized catalyst were studied via FTIR

Agar-entrapped sulfonated DABCO: Agelly acidic catalyst for the acceleration of one-pot synthesis of 1,2,4-triazoloquinazolinone and some pyrimidine derivatives

In this project, a recently synthesized DABCO-based catalyst is entrapped in agar to reduce its moisture sensitivity leading to enhancement of its stability and catalytic activity. After preparation and identification this new reagent is used as an efficient and environmentally safe catalyst for the preparation of 1, 2, 4-triazoloquinazolinone and some pyrimidine derivatives. This method is accompanied with some superiorities such as, simple operation, mild and green conditions, use of low cost and non-hazardous natural material, short reaction times, easy preparation methods and simple work-up procedures. The prepared catalyst can be re-used for several times in all of the studied reactions without any appreciable loss in its activity.

A highly efficient and green approach for the synthesis of pyrimido[4,5-b]quinolines using N,N-diethyl-N-sulfoethanaminium chloride

A highly efficient and green protocol for the synthesis of pyrimido[4,5-b]quinolines has been described. The one-pot multicomponent reaction of dimedone with arylaldehydes and 6-amino-1,3-dimethyluracil in the presence of N,N-diethyl-N-sulfoethanaminium c

Preparation, characterization and application of nano-[Fe3O4?-SiO2?R-NHMe2][H2PO4] as a novel magnetically recoverable catalyst for the synthesis of pyrimido[4,5-b]quinolines

A novel organic-inorganic hybrid magnetic nanomaterial namely nano-[Fe3O4?-SiO2?R-NHMe2][H2PO4] (nano-[FSRN][H2PO4]) has been prepared, and characterized by FT-IR, EDS

Dicationic ionic liquid grafted with silica-coated nano-Fe3O4 as a novel and efficient catalyst for the preparation of uracil-containing heterocycles

Abstract: Bisulfate-functionalized dicationic ionic liquid grafted with silica-coated nano-Fe3O4 (nano-[Fe3O4@SiO2@BDIL] or NFSBDI) was synthesized as a novel nanomagnetic material, and its structure

A novel organic-inorganic hybrid material: Production, characterization and catalytic performance for the reaction of arylaldehydes, dimedone and 6-amino-1,3-dimethyluracil

A novel silica-based organic-inorganic hybrid material namely N,N,N′,N′-tetramethyl-N-(silica-n-propyl)-N′-sulfonic acid-ethylenediaminium chloride/mesylate ([TSSECM]) was prepared, and characterized by EDS (energy-dispersive X-ray spectroscopy), FE-SEM (

Preparation of a new DABCO-based ionic liquid and investigation on its application in the synthesis of benzimidazoquinazolinone and pyrimido[4,5-b]-quinoline derivatives

In this article, we report the preparation of a new ionic liquid from the reaction of DABCO and sulfuric acid and its characterization using FT-IR, Mass and NMR spectroscopy. This ionic liquid is air- and water-stable and affordable. Afterward this reagen

An eco-friendly and magnetized biopolymer cellulose-based heterogeneous acid catalyst for facile synthesis of functionalized pyrimido[4,5-b]quinolines and indeno fused pyrido[2,3-d]pyrimidines in water

Abstract: A cellulose-based magnetic nano-composite supported SO3H group was synthesized and characterized using Fourier transform infrared spectroscopy, energy-dispersive X-ray spectroscopy, thermogravimetric analysis, X-ray diffraction, and scanning electron microscopy. Thereafter, its capability to promote the one-pot, three-component synthesis of pyrimido [4,5-b] quinolone and pyrido [2,3-d] pyrimidine derivatives was evaluated. The obtained results are indicative of excellent yields and short reaction times. The biopolymer based catalyst is readily recovered and reused several times without a decrease in yield. Graphical Abstract: [Figure not available: see fulltext.]

A New MCR strategy generating a collection of skeletally diverse simple molecules combinatorially

Background: 1,4 Dihydropyridines (1,4 DHPs), chromeno[4,3-b] quinolines and pyrimido [4,5-b]quinolines are biologically and pharmaceutically important heterocycles. They are also present in many natural products. Many methods have been applied for their s

Multicomponent synthesis of some benzo, pyrimido and pyrazolo fused heterocycles using [Nmp]H2Po4 as an efficient reaction medium

An efficient synthesis of benzoxanthene, pyrimidoquinoline, pyrimidochromene and pyrazolopyridine fused heterocycles by condensation of aromatic aldehydes, 2- hydroxy-1,4-naphthoquinone/ 6-amino-1,3-dimethyl uracil/ 1,3-dimethyl barbituric acid/ 5-amino-3-methyl-1-phenylpyrazole and 5,5-dimethylcyclohexane-1,3-dione/5- methylcyclohexane-1,3-dione/ cyclohexane-1,3-dione/cyclopentane-1,3-dione has been developed using [NMP]H2PO4 as a highly efficient reaction medium and catalyst. All the reactions proceeded smoothly and gave corresponding products in high yield after a simple workup.