81064-05-3

Upstream product

• 79619-11-7 4-(Carboxymethyl)-4-(2,3-dimethoxyphenyl)-1-methyl-3-methylene-2-piperidinone 
• 81012-10-4 imidazolide of 4-(carboxymethyl)-4-(2,3-dimethoxyphenyl)-1-methyl-3-methylene-2-piperidinone 
• 81012-11-5 tert-butyl 4-(2,3-dimethoxyphenyl)-4-<4-(1-methyl-3-methylene-2-oxopiperidinyl)>-3-oxobutyrate 
• 81012-12-6 tert-butyl trans-4a-(2,3-dimethoxyphenyl)-1,6-dioxo-2-methyl-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-7-carboxylate 

Downstream Products

• 81012-13-7 trans-4a-(2,3-dimethoxyphenyl)-6,6-(ethylenedioxy)-2-methyl-1-oxo-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline 
• 81012-18-2 cis-6,6-(ethylenedioxy)-4a-(2-hydroxy-3-methoxyphenyl)-2-methyl-1-oxo-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline 
• 81012-14-8 trans-4a-(2,3-dimethoxyphenyl)-6,6-(ethylenedioxy)-2-methyl-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline 
• 81012-15-9 trans-4a-(2,3-dimethoxyphenyl)-2-methyl-6-oxo-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline 

Relevant academic research and scientific papers

Codeine Analogues. Synthesis of 4a-(2,3-Dimethoxyphenyl)decahydroisoquinolines and Octahydro-1H-benzopyranoisoquinolines

Extension of our methods for the synthesis of phenyl- and (m-methoxyphenyl)decahydroisoquinolines to the 2,3-dimethoxyphenyl series is presented.Surprisingly, direct extrapolation of the previous methodology was frequently not possible, as the dimethoxyph