810668-53-2

Usage

Uses

Used in Dietary Supplements and Functional Foods:
(4Z,7S,8E,10Z,12E,14E,16R,17S,19Z)-methyl 7,16,17-trihydroxydocosa-4,8,10,12,14,19-hexaenoate is used as a dietary supplement and functional food ingredient for its potential health benefits, including anti-inflammatory and cardiovascular protective properties. DHA and its derivatives have been linked to improved cognitive function and brain health, making it a valuable addition to these products.

Upstream product

• 6089-09-4 4-pentynoic acid 
• 810668-39-4 oct-7-en-4-ynoic acid 
• 810668-50-9 (4Z,8E,12E,14E)-(S)-15-[(4R,5S)-2,2-Dimethyl-5-((Z)-pent-2-enyl)-[1,3]dioxolan-4-yl]-7-triethylsilanyloxy-pentadeca-4,8,12,14-tetraen-10-ynoic acid methyl ester 
• 810668-51-0 (S,4Z,8E,12E,14E)-methyl 15-((4R,5S)-2,2-dimethyl-5-((Z)-pent-2-en-1-yl)-1,3-dioxolan-4-yl)-7-hydroxypentadeca-4,8,12,14-tetraen-10-ynoate 
• 810668-44-1 (S)-7,8-Bis-triethylsilanyloxy-oct-4-ynoic acid methyl ester 
• 810668-45-2 (Z)-(S)-7,8-Bis-triethylsilanyloxy-oct-4-enoic acid methyl ester 
• 810668-38-3 (4Z,8E)-(S)-9-Iodo-7-triethylsilanyloxy-nona-4,8-dienoic acid methyl ester 
• 810668-48-5 {(3E,5E)-6-[(4R,5S)-2,2-Dimethyl-5-((Z)-pent-2-enyl)-[1,3]dioxolan-4-yl]-hexa-3,5-dien-1-ynyl}-trimethyl-silane 
• 810668-46-3 (Z)-(S)-8-Oxo-7-triethylsilanyloxy-oct-4-enoic acid methyl ester 
• 810668-49-6 (4R,5S)-4-((1E,3E)-Hexa-1,3-dien-5-ynyl)-2,2-dimethyl-5-((Z)-pent-2-enyl)-[1,3]dioxolane 
• 810668-42-9 (S)-7,8-Dihydroxy-oct-4-ynoic acid methyl ester 
• 810668-40-7 oct-7-en-4-ynoic acid methyl ester 
• 810668-41-8 6-oxiranyl-hex-4-ynoic acid methyl ester 
• 97514-88-0 [2(E)-5-(trimethylsilyl)pent-2-en-4-ynyl]triphenylphosphonium bromide 

Downstream Products

• 810668-37-2 (4Z,7S,8E,10Z,12E,14E,16R,17S,19Z)-7,16,17-trihydroxydocosa-4,8,10,12,14,19-hexaenoic acid 

Relevant academic research and scientific papers

COMPOSITIONS AND METHODS RELATING TO SALTS OF SPECIALIZED PRO-RESOLVING MEDIATORS OF INFLAMMATION

The present invention relates to compounds of Formulas I-IV, which are salts of special lipid mediators of inflammation, compositions containing same, and methods of using same in the treatment of various diseases and disorders characterized by chronic or excessive inflammation, or both.

First total synthesis of 7(S),16(R),17(S)-Resolvin D2, a potent anti-inflammatory lipid mediator

A total synthesis of a biological highly active lipid mediator derived from docosahexaenoic acid is described. The first total synthesis of 7(S),16(R),17(S)-Resolvin D2, a lipid mediator derived from docosahexaenoic acid, has been achieved. The key features of our synthetic strategy encompass a Co-salen hydrolytic kinetic resolution of a terminal epoxide combined with a chiral pool strategy.