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1-(2-chloroethyl)-3-[2-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-(methylsulfanyl)ethyl]-1-nitrosourea, also known as nimustine, is a chemotherapeutic agent derived from the class of alkylating agents. It is characterized by its ability to interfere with the DNA of cancer cells, thereby preventing their replication and inducing cell death. Despite its high toxicity and potential for serious side effects, nimustine remains a valuable option in the treatment of certain cancers when other treatments have failed.

81068-96-4

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81068-96-4 Usage

Uses

Used in Anticancer Applications:
Nimustine is employed as an anticancer agent, particularly in the treatment of brain tumors and malignant melanoma. It modulates the DNA of cancer cells, inhibiting their growth and proliferation. Although it is highly toxic and can cause severe side effects such as bone marrow suppression and an increased risk of secondary malignancies, its efficacy in specific cancer types has been demonstrated in clinical trials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, nimustine is used as a chemotherapeutic agent for the development of cancer treatment regimens. Its application in this industry is due to its demonstrated effectiveness in treating certain types of cancers, even when other treatment options have been unsuccessful. However, its use is carefully considered due to its high toxicity and potential side effects.
Used in Clinical Trials:
Nimustine is also utilized in clinical trials to evaluate its safety, efficacy, and potential for use in combination with other treatments. These trials aim to determine the optimal dosage and administration methods, as well as to identify any additional side effects or risks associated with its use. The application of nimustine in clinical trials is crucial for advancing cancer treatment options and improving patient outcomes.

Check Digit Verification of cas no

The CAS Registry Mumber 81068-96-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,0,6 and 8 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 81068-96:
(7*8)+(6*1)+(5*0)+(4*6)+(3*8)+(2*9)+(1*6)=134
134 % 10 = 4
So 81068-96-4 is a valid CAS Registry Number.

81068-96-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chloroethyl)-3-[2-(5-fluoro-2,4-dioxopyrimidin-1-yl)-2-methylsulfanylethyl]-1-nitrosourea

1.2 Other means of identification

Product number -
Other names urea,n-(2-chloroethyl)-n'-[2-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2h)-pyrimidinyl)-2-(methylthio)ethyl]-n-nitroso

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:81068-96-4 SDS

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