810682-47-4

Upstream product

• 108-24-7 acetic anhydride 
• 810682-46-3 (S)-1-Hydroxymethyl-3-iodo-2,2,4-trimethyl-cyclohex-3-enol 
• 810682-20-3 (S)-7-Iodo-2,2,6,6,8-pentamethyl-1,3-dioxa-spiro[4.5]dec-7-ene 

Downstream Products

• 810682-49-6 Acetic acid (S)-3-iodo-1-methoxymethoxy-2,2,4-trimethyl-cyclohex-3-enylmethyl ester 
• 810682-32-7 (S)-3-iodo-1-methoxymethoxy-2,2,4-trimethyl-cyclohex-3-enecarbaldehyde 
• 810682-38-3 ((S)-3-Iodo-1-methoxymethoxy-2,2,4-trimethyl-cyclohex-3-enyl)-methanol 

Relevant academic research and scientific papers

Development of silicon-tethered anionic reaction and its application to the synthesis of chiral A-ring moieties of Taxol

Silicon-tethered intramolecular nucleophilic additions of a hydroxymethyl unit to ketones in β-hydroxyketones have been developed. The product obtained by this protocol was successfully converted to chiral A-ring moieties of Taxol. Also developed was a pr