81086-53-5Relevant academic research and scientific papers
Oxo-ester mediated native chemical ligation: Concept and applications
Wan, Qian,Chen, Jin,Yuan, Yu,Danishefskr, Samuel J.
supporting information; scheme or table, p. 15814 - 15816 (2009/05/16)
A direct oxo-ester peptide ligation method has been developed. Through the use of an activated C-terminal para nitrophenyl ester (1), it is possible to achieve direct cysteine ligations (1 + 2 → 4). Peptide substrates incorporating bulky C-terminal amino acids (1) can be accommodated with high reaction efficiency. Copyright
