81096-77-7Relevant academic research and scientific papers
Deracemizing organocatalyzed Michael addition reactions of 2-(arylthio)cyclobutanones with β-nitrostyrenes
Luridiana, Alberto,Frongia, Angelo,Aitken, David J.,Guillot, Regis,Sarais, Giorgia,Secci, Francesco
, p. 3394 - 3403 (2016)
Organocatalyzed Michael addition reactions of 2-(arylthio)cyclobutanones with trans-β-nitrostyrenes have been carried out using a bifunctional thiourea-primary amine catalyst, providing diastereoisomerically and enantiomerically enriched 2-alkyl-2-(arylthio)cyclobutanones having two contiguous stereocenters of which one is a chiral quaternary center. The absolute configuration of these novel adducts was assigned by X-ray diffraction analysis and a transition-state model is proposed to explain the observed stereoselectivities.
Cycloadditions of Ynamines with α,β-Unsaturated Sulfones: Approach to Versatile Four-Membered Carbocyclic Intermediates
Eisch, John J.,Galle, James E.,Hallenbeck, Lawrence E.
, p. 1608 - 1610 (2007/10/02)
The interaction of ynamines with various α,β-unsaturated sulfones, such as 1-alkenyl, 1-alkynyl, or 1,3-alkadienyl sulfones, leads to the ready formation of the vicinally amino- and sulfonyl-substituted cyclobuta ring in a regiospecific manner.The resulti
