81099-45-8

Basic information

• Product Name: 1,4-bis-{[2-(di(2-hydroxyethyl)amino)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione
• Synonyms: 1,4-bis-{[2-(di(2-hydroxyethyl)amino)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione
• CAS NO: 81099-45-8
• Molecular Weight: 532.594
• Mol File: 81099-45-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,4-bis-{[2-(di(2-hydroxyethyl)amino)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-bis-{[2-(di(2-hydroxyethyl)amino)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione(81099-45-8)
• EPA Substance Registry System: 1,4-bis-{[2-(di(2-hydroxyethyl)amino)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione(81099-45-8)

Safety Data

• Hazardous Substances Data: 81099-45-8(Hazardous Substances Data)

Upstream product

• 23478-60-6 leuco-1,4,5,8-tetrahydroxyanthraquinone 

Relevant articles and documents

Anti-cancer compounds

Compounds of formula (I) STR1 in which R1, R2, R3 and R4 are each separately selected from hydrogen, X, NH--A--NHR and NH--A--N(O)R'R" wherein X is hydroxy, halogeno, amino, C1-4 alkoxy or C2-8 alkanoyloxy, A is a C2-4 alkylene group with a chain length between NH and NHR or N(O)R'R" of at least 2 carbon atoms and R, R' and R" are each separately selected from C1-4 alkyl groups and C2-4 hydroxyalkyl and C2-4 dihydroxyalkyl groups in which the carbon atom attached to the nitrogen atom does not carry a hydroxy group and no carbon atom is substituted by two hydroxy groups, or R' and R" together are a C2-6 alkylene group which with the nitrogen atom to which R" and R" are attached forms a heterocyclic group having 3 to 7 atoms in the ring, but with the proviso that at least one of R1 to R4 is a group NH--A--N(O)R'R", and physiologically acceptable salts thereof are of value in the treatment of cancer.