81115-40-4Relevant academic research and scientific papers
Hydroxyphenyl-1-methylpyridinium-iodide as Potential Reactivators of Acetylcholinesterase Poisoned with Organophosphorus Compounds
Riggio, Gaetano,Hopff, Wolfgang Herbert,Hofmann, Alfred Andre,Waser, Peter Gaudenz
, p. 1039 - 1045 (2007/10/02)
It was our aim to reactivate acetylcholinesterase poisoned with sarin.We synthesized 2-(o-hydroxyphenyl)-1-methylpyridinium-iodide (9), 2-(p-hydroxyphenyl)-1-methylpyridinium-iodide (19) and 4-(o-hydroxyphenyl)-1-methylpyridinium-iodide (14) as potential reactivators.All substances showed moderate toxicity against mice; their reactivity potency in vitro and in vivo was negligible.
Intramolecular Addition of Enolates to Pyridinium Ions: Formation of Spiro
Weller, Dwight D.,Luellen, Glenn R.,Weller, Doreen L.
, p. 3061 - 3067 (2007/10/02)
Intramolecular addition of ketone and ester enolates to N-alkylpyridinium species produced spiro in 82-93percent yields.When the ketone adducts were treated with hydriodic acid in ethanol at room temperature and the est
